Nitescu Bogdan, Dumitrescu Andrei, Stanescu Florin Radu, Cintacioiu Diana, Lates Gratiana, Parasca Sorin Viorel
Faculty of Medicine, University of Medicine and Pharmacy "Carol Davila", 050474 Bucharest, Romania.
Clinical Emergency Hospital of Plastic, Reconstructive Sugery and Burns, 050474 Bucharest, Romania.
Medicina (Kaunas). 2025 Apr 17;61(4):744. doi: 10.3390/medicina61040744.
Dermal matrices have brought solutions for many problems, mainly in the treatment of burns and burn scar revisions. The objective of this study was to draw attention to the limits of a collagen-elastin dermal matrix (MatriDerm) in its 1 mm variant for the treatment of burn scars on the face and neck. A case series of four patients (three women and one man) with burn scars of the face (one case) and of the neck (three cases) treated with collagen-elastin matrices is presented. In all cases, the excision or release of the scars was performed, and the defects were covered with MatriDerm and thin split-thickness skin grafts in the same operative time. In all cases, the graft take was very good but was followed by the important contraction of the graft to such an extent that the results were found to be poor by both the surgeons and the patients. The surface of the new scar was irregular, and the elasticity was low. The article points out some probable causes and draws attention to the need for more objective studies regarding the use of this dermal matrix in burn scars of the head and neck. This collagen-elastin 1 mm dermal matrix should be used with caution for the surgical treatment of burn scars of the head and neck area, and its indication should be carefully weighted.
真皮基质为许多问题带来了解决方案,主要用于烧伤治疗和烧伤瘢痕修复。本研究的目的是提醒人们注意一种1毫米厚的胶原-弹性蛋白真皮基质(MatriDerm)在治疗面部和颈部烧伤瘢痕方面的局限性。本文介绍了一组4例(3名女性和1名男性)面部(1例)和颈部(3例)烧伤瘢痕患者使用胶原-弹性蛋白基质治疗的病例。所有病例均进行了瘢痕切除或松解,并在同一手术时间用MatriDerm和薄断层皮片覆盖缺损。所有病例中,植皮成活情况良好,但随后植皮出现严重收缩,以至于外科医生和患者都认为效果不佳。新瘢痕表面不规则,弹性差。文章指出了一些可能的原因,并提醒人们需要对这种真皮基质在头颈部烧伤瘢痕治疗中的应用进行更客观的研究。这种1毫米厚的胶原-弹性蛋白真皮基质在头颈部烧伤瘢痕的手术治疗中应谨慎使用,其适应证应仔细权衡。