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阳光金奇异果与心理健康(GoKiPH):一项随机对照交叉试验。

SunGold Kiwifruit and Psychological Health (GoKiPH): A Randomised Controlled Crossover Trial.

作者信息

Billows Michael, Kakoschke Naomi, Zajac Ian T

机构信息

Human Health, Health and Biosecurity, CSIRO, Adelaide, SA 5000, Australia.

School of Psychology, University of Adelaide, Adelaide, SA 5005, Australia.

出版信息

Nutrients. 2025 Apr 18;17(8):1375. doi: 10.3390/nu17081375.

DOI:10.3390/nu17081375
PMID:40284237
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC12030757/
Abstract

The consumption of SunGold kiwifruit, a fruit rich in vitamin C, has been associated with improved mood in healthy individuals with low vitamin C levels. However, no studies have examined this relationship in individuals with elevated mood disturbance. This study examined the potential for SunGold kiwifruit to improve psychological wellbeing in mood-disturbed adults. This study was a two-period, non-blinded crossover trial. Adults ( = 26) aged 18-60 years with mild to moderate mood disturbance were randomised with a two-week washout between periods. During each 4-week period, participants consumed either two SunGold kiwifruit daily or their usual diet. The primary outcome was mean change in total mood disturbance scores from the kiwifruit period compared to the diet-as-usual period. Secondary outcomes were blood plasma vitamin C concentration, wellbeing, vitality and gastrointestinal symptoms. Participants and researchers were unblinded to condition and intervention. Scores for total mood disturbance (65.2%, < 0.001), wellbeing (10.5%, < 0.01) and vitality (17.3%, = 0.001) significantly improved in the kiwifruit condition compared to the usual diet. Vitamin C (27.5%, = 0.002) concentrations also improved and gastrointestinal symptom reduction was evident during kiwifruit consumption (16.2%, = 0.003). There were no serious adverse events. SunGold kiwifruit consumption resulted in significant reductions in total mood disturbance scores and improvements in wellbeing, vitality and vitamin C concentrations. Gastrointestinal symptom severity also significantly reduced. Results provide preliminary evidence of the potential benefits of kiwifruit for reducing mood disturbance in adult populations. Further studies in diverse groups, including clinical populations, are warranted.

摘要

食用富含维生素C的阳光金果猕猴桃,与维生素C水平较低的健康个体的情绪改善有关。然而,尚无研究在情绪障碍加剧的个体中考察这种关系。本研究探讨了阳光金果猕猴桃改善情绪障碍成年人心理健康的潜力。本研究为两阶段、非盲交叉试验。18至60岁、有轻度至中度情绪障碍的成年人( = 26)被随机分组,两阶段之间有两周的洗脱期。在每个为期4周的阶段中,参与者每天食用两个阳光金果猕猴桃或其日常饮食。主要结局是与日常饮食阶段相比,猕猴桃阶段总情绪障碍评分的平均变化。次要结局包括血浆维生素C浓度、幸福感、活力和胃肠道症状。参与者和研究人员对状况和干预措施不设盲。与日常饮食相比,猕猴桃组的总情绪障碍评分(65.2%, < 0.001)、幸福感(10.5%, < 0.01)和活力(17.3%, = 0.001)显著改善。维生素C浓度(27.5%, = 0.002)也有所提高,食用猕猴桃期间胃肠道症状明显减轻(16.2%, = 0.003)。未出现严重不良事件。食用阳光金果猕猴桃可显著降低总情绪障碍评分,并改善幸福感、活力和维生素C浓度。胃肠道症状严重程度也显著降低。结果为猕猴桃对减少成年人群情绪障碍的潜在益处提供了初步证据。有必要在包括临床人群在内的不同群体中开展进一步研究。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/4d5c/12030757/cdd944ff4090/nutrients-17-01375-g004a.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/4d5c/12030757/ff54b5c7d3f8/nutrients-17-01375-g001.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/4d5c/12030757/ec8cbac22168/nutrients-17-01375-g002.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/4d5c/12030757/ea671939ca9a/nutrients-17-01375-g003.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/4d5c/12030757/cdd944ff4090/nutrients-17-01375-g004a.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/4d5c/12030757/ff54b5c7d3f8/nutrients-17-01375-g001.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/4d5c/12030757/ec8cbac22168/nutrients-17-01375-g002.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/4d5c/12030757/ea671939ca9a/nutrients-17-01375-g003.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/4d5c/12030757/cdd944ff4090/nutrients-17-01375-g004a.jpg

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Antioxidants (Basel). 2024 Feb 23;13(3):272. doi: 10.3390/antiox13030272.
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Major depressive disorder.重度抑郁症。
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Tryptophan Metabolism in Depression: A Narrative Review with a Focus on Serotonin and Kynurenine Pathways.抑郁症中的色氨酸代谢:一篇以 5-羟色胺和犬尿氨酸途径为重点的叙述性综述。
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Effectiveness of dietary interventions in mental health treatment: A rapid review of reviews.饮食干预对心理健康治疗的有效性:综述的快速回顾。
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A Possible Antidepressive Effect of Dietary Interventions: Emergent Findings and Research Challenges.饮食干预可能具有的抗抑郁作用:新发现与研究挑战
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