Hsueh Fu-Chun, Chien Chia-Yi, Chang Shu-Wei, Lian Bo-Rong, Lin Hong-Yao, Ellerma Leonardo, Chiou Ming-Tang, Lin Chao-Nan
Department of Veterinary Medicine, College of Veterinary Medicine, National Pingtung University of Science and Technology, Pingtung 91201, Taiwan.
Intervet Animal Health Taiwan Ltd., Taipei 11047, Taiwan.
Vet Sci. 2025 Mar 26;12(4):304. doi: 10.3390/vetsci12040304.
Porcine circovirus type 2 (PCV2) and (MHP) are both important and common pathogens in the pig industry. Both pathogens are major contributors to the porcine respiratory disease complex and serve to potentiate other bacterial infections such as . This study aims to evaluate the efficacy of a ready-to-use bivalent PCV2 and MHP vaccine in the field under naturally PCV2-infected farms against existing monovalent options. We evaluated PCV2 viremia, PCV2 antibodies, and lung lesion scores in slaughtered pigs in our study across four farms in Taiwan. Our results found that in two out of four farms, the piglets vaccinated with Porcilis PCV M Hyo had superior whole-life PCV2 viremia reduction compared to the existing vaccination program on farms. In the lung lesion scoring, the Porcilis PCV M Hyo group had significantly lower -type lesions in pigs than in the competitor group in two out of three farms evaluated. In this field trial, Porcilis PCV M Hyo proved to be efficacious in protecting piglets against both PCV2 viremia and the impact of MHP secondary infection, in the context of a reduction in viremia and reduced APP-like lesions found at slaughter.
猪圆环病毒2型（PCV2）和猪支原体肺炎（MHP）都是养猪业中重要且常见的病原体。这两种病原体都是猪呼吸道疾病综合征的主要促成因素，并会增强其他细菌感染，如[此处原文缺失具体细菌名称]。本研究旨在评估一种即用型PCV2和MHP二价疫苗在自然感染PCV2的猪场中相对于现有单价疫苗的田间效果。我们在台湾的四个猪场对屠宰猪的PCV2病毒血症、PCV2抗体和肺部病变评分进行了评估。我们的结果发现，在四个猪场中的两个，与猪场现有的疫苗接种方案相比，接种了Porcilis PCV M Hyo疫苗的仔猪在整个生命周期内PCV2病毒血症的降低效果更好。在肺部病变评分方面，在评估的三个猪场中的两个，Porcilis PCV M Hyo组猪的[此处原文缺失具体病变类型]病变明显低于竞争组。在该田间试验中，Porcilis PCV M Hyo在降低病毒血症以及减少屠宰时发现的类APP病变的情况下，被证明在保护仔猪免受PCV2病毒血症和MHP继发感染影响方面是有效的。
