Matache Vasilache Elena-Roxana, Gurau Gabriela, Raileanu Cosmin-Raducu, Zaharescu Anamaria, Popa Gabriel Valeriu, Maftei Nicoleta-Maricica, Busila Camelia, Matei Madalina Nicoleta, Tutunaru Dana
Department of Morphological and Functional Sciences, Faculty of Medicine and Pharmacy, "Dunarea de Jos" University, 800008 Galati, Romania.
Medical Laboratory Department, "Sf. Ioan" Emergency Clinical Hospital for Children, 800494 Galati, Romania.
Viruses. 2025 Apr 19;17(4):586. doi: 10.3390/v17040586.
Respiratory infections are the most common infectious diseases among children, representing a cause of death and generating a significant number of hospitalisations. The aim of the study was to analyse the epidemiological and clinical characteristics of viral pathogens causing respiratory tract infections in newborns and young children admitted to Galati pediatric hospital between October 2022 and December 2023. The diagnosis was performed using multiplex RT-PCR panels, which allowed simultaneous identification of respiratory pathogens (viruses and bacteria). From a total of 803 hospitalised patients with respiratory diseases, 607 (75.6%) children had a positive result for at least one respiratory virus and 96 patients (11.9%) were identified with bacterial infections. Mixed coinfections were found in almost half of the patients (44.5%). Most of RSV positive children had an increased length of stay, more than 7 days. It was shown a decline in severe cases of viral respiratory infections with prolonged hospitalisation as patients age up to 5 years.
呼吸道感染是儿童中最常见的传染病，是导致死亡的一个原因，且造成大量住院病例。本研究的目的是分析2022年10月至2023年12月期间入住加拉茨儿科医院的新生儿和幼儿中引起呼吸道感染的病毒病原体的流行病学和临床特征。诊断采用多重逆转录聚合酶链反应（RT-PCR）检测板进行，可同时鉴定呼吸道病原体（病毒和细菌）。在总共803例住院的呼吸道疾病患者中，607例（75.6%）儿童至少有一种呼吸道病毒检测呈阳性，96例患者（11.9%）被鉴定为细菌感染。近一半的患者（44.5%）发现有混合感染。大多数呼吸道合胞病毒（RSV）阳性儿童住院时间延长，超过7天。结果显示，随着患者年龄增长至5岁，病毒呼吸道感染的严重病例数随着住院时间延长而下降。
