Black D M, Daniels A U, Dunn H K, Kruger R A
Clin Orthop Relat Res. 1985 Sep(198):259-63.
Computerized tomography (CT) provides the capability to determine vertebral bone density with a high degree of accuracy and precision, detecting density changes as small as 5% in serial testing. In this pilot study, CT was used to determine the effects of total hip arthroplasty and its consequent alterations in physical activity levels on the vertebral bone density of 13 postoperative patients. Vertebral bone density was also evaluated in six preoperative patients with degenerative joint disease of the hip and five control patients. The preoperative group and controls were then compared with the postoperative patients, who were divided into two groups--those who had achieved good activity levels and those whose levels of activity remained poor. CT measurement of bone density in the central bodies of T12, L1, and L2 showed that the preoperative group was similar to controls. This suggests that patients accept total hip arthroplasty rather than endure significant activity limitations for extended periods of time. When activity level was restored by arthroplasty, vertebral bone density was preserved. If the patient continued at a poor activity level postoperation, significant loss of bone density occurred secondary to disuse.
计算机断层扫描(CT)能够高度准确且精确地测定椎骨骨密度,在连续检测中能检测到低至5%的密度变化。在这项初步研究中,CT被用于确定全髋关节置换术及其导致的身体活动水平变化对13名术后患者椎骨骨密度的影响。还对6名术前患有髋关节退行性关节疾病的患者和5名对照患者的椎骨骨密度进行了评估。然后将术前组和对照组与术后患者进行比较,术后患者被分为两组——活动水平良好的患者和活动水平仍然较差的患者。对T12、L1和L2椎体中心的骨密度进行CT测量显示,术前组与对照组相似。这表明患者接受全髋关节置换术,而不是长时间忍受明显的活动受限。当通过置换术恢复活动水平时,椎骨骨密度得以保留。如果患者术后活动水平持续较差,由于废用会发生明显的骨密度丢失。