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西班牙腹膜透析使用量超过血液透析的预算影响。

Budgetary impact of increasing use of peritoneal dialysis over haemodialysis in Spain.

作者信息

Barbado Gemma, Garí Carla, Ariznavarreta Asís, Vidal-Vilar Neus, Alvarez Carlos

机构信息

Associate Director Government Affairs and Market Access Spain and Portugal, Baxter S.L., Madrid, Spain.

Outcomes´10 (a ProductLife Group Company), Castellón, Spain.

出版信息

Health Econ Rev. 2025 Apr 26;15(1):39. doi: 10.1186/s13561-025-00633-8.

Abstract

BACKGROUND

Chronic kidney disease (CKD) represents a significant public health concern, due to its high prevalence and incidence, as well as its substantial socio-economic costs. In Spain, estimates suggest that the direct healthcare costs of CKD will increase by 13.8% from 2022, which is why the cost of kidney replacement treatment (KRT) programs efficiency and sustainability is under constant analysis. Our analysis aimed to estimate the cost associated with peritoneal dialysis (PD) compared to hemodialysis (HD) from the Spanish National Health System (NHS) perspective and to evaluate the budgetary impact of an increase in the use of PD in our healthcare system environment.

METHODS

The number of patients eligible for KRT was calculated based on the total Spanish population and the incidence and prevalence of patients with end-stage renal disease (ESRD). Patients receiving each modality, type of dialysis, and location of dialysis were estimated. The annual costs of each dialysis modality were calculated and included the cost of dialysis sessions and additional costs (including the cost of peritoneal and vascular access, hospitalisation costs due to potential complications of dialysis, cost of health care personnel, and cost of health care transport used by patients). Population data and costs (€, 2024) were obtained from the Spanish databases and a nephrologist validated the assumptions. Budget impact analysis assessed the incremental budget impact between the current scenario and the alternative scenario, where 30% of incident patients on scheduled HD would receive PD.

RESULTS

We estimated that in Spain, there are 27,281 prevalent dialysis patients (3,141 receiving PD and 24,140 receiving HD/HDF) and 6,052 incident dialysis patients (1,173 receiving PD and 4,879 HD/HDF). The cost of dialysis amount to €1,555,573,771 (€141,361,374 PD and €1,414,212,397 to HD) in the current scenarios and to €1,540,584,011 (€167,593,157 PD and €1,372,990,854 HD) in the alternative scenario, resulting in a saving of €14,989,760 when 30% of the patients scheduled to receive HD would instead receive PD during the first year.

CONCLUSIONS

The increased use of PD in Spain improves the system's efficiency, generating significant savings in the treatment of ESRD patients from the NHS perspective.

摘要

背景

慢性肾脏病(CKD)因其高患病率、高发病率以及巨大的社会经济成本,成为一个重大的公共卫生问题。在西班牙,据估计,CKD的直接医疗费用自2022年起将增长13.8%,这就是为什么肾脏替代治疗(KRT)项目的成本效益和可持续性一直在分析之中。我们的分析旨在从西班牙国家卫生系统(NHS)的角度估算与腹膜透析(PD)相比血液透析(HD)的相关成本,并评估在我们的医疗系统环境中增加PD使用量的预算影响。

方法

根据西班牙总人口以及终末期肾病(ESRD)患者的发病率和患病率计算符合KRT条件的患者数量。估算接受每种透析方式、透析类型及透析地点的患者人数。计算每种透析方式的年度成本,包括透析疗程成本及其他成本(包括腹膜和血管通路成本、透析潜在并发症导致的住院成本、医护人员成本以及患者使用的医疗运输成本)。人口数据和成本(2024年欧元)取自西班牙数据库,且一名肾病专家对假设进行了验证。预算影响分析评估了当前情景与替代情景之间的增量预算影响,在替代情景中,30%计划接受HD的新发病患者将接受PD。

结果

我们估计,在西班牙,有27281名透析现患患者(3141名接受PD,24140名接受HD/HDF)以及6052名透析新发病患者(1173名接受PD,4879名接受HD/HDF)。在当前情景下,透析成本总计1555573771欧元(PD为141361374欧元,HD为1414212397欧元),在替代情景下为1540584011欧元(PD为167593157欧元,HD为1372990854欧元),当30%计划接受HD的患者在第一年转而接受PD时,可节省14989760欧元。

结论

在西班牙增加PD的使用可提高系统效率,从NHS的角度来看,能在ESRD患者的治疗中节省大量费用。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/8a46/12032717/9d95dc97b0ed/13561_2025_633_Fig1_HTML.jpg

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