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β-连接的2-脱氧糖的立体选择性合成方法。

Stereoselective Approaches to β-Linked 2-Deoxy Sugars.

作者信息

Bennett Clay S

机构信息

Department of Chemistry, Tufts University, 62 Talbot Ave, Medford, MA 02155, USA.

出版信息

Molecules. 2025 Apr 1;30(7):1578. doi: 10.3390/molecules30071578.

DOI:10.3390/molecules30071578
PMID:40286171
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC11990799/
Abstract

This review presents a survey of recent developments in the synthesis of β-linked 2-deoxy sugars. Approaches ranging from catalysis to de novo synthesis are described, with a focus on methods developed in the last 10 years. Where relevant, the application of these technologies to synthesis and mechanistic information is discussed. Finally, it concludes with an examination of the scope and limitations of these technologies, as well as examinations about where the field should head next.

摘要

本综述介绍了β-连接的2-脱氧糖合成的近期进展。描述了从催化到从头合成的各种方法,重点是过去10年中开发的方法。在相关情况下,讨论了这些技术在合成中的应用和机理信息。最后,对这些技术的范围和局限性进行了考察,并探讨了该领域未来的发展方向。

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