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一种基于喹啉衍生物的新型铁荧光传感器。

A Novel Fluorescent Sensor for Fe Based on a Quinoline Derivative.

作者信息

Zhang Xinru, Sun Bo, Zhang Huan, Zhou Chen, Pan Qingqing, Wang Yining, Zou Chenyang, Hou Juan, Sun Jing

机构信息

School of Chemistry & Environmental Engineering, Jilin Provincial International Joint Research Center of Photo-Functional Materials and Chemistry, Changchun University of Science and Technology, Changchun 130022, China.

China National Petroleum Corporation Hohhot Petrochemical Branch, Hohhot 010010, China.

出版信息

Molecules. 2025 Apr 1;30(7):1579. doi: 10.3390/molecules30071579.

Abstract

A new fluorescent sensor for detecting Fe was developed based on chemical modification of the quinoline group. Titration experiments showed that the sensor exhibits high selectivity and sensitivity toward Fe, even in complex systems. The recognition mechanism was verified through theoretical calculations, demonstrating that the sensor can perform qualitative and quantitative analysis on Fe. The cell imaging and zebrafish imaging experiments further prove the potential application of the sensor in the field of bioluminescence imaging.

摘要

基于喹啉基团的化学修饰开发了一种用于检测铁的新型荧光传感器。滴定实验表明,该传感器即使在复杂体系中对铁也表现出高选择性和高灵敏度。通过理论计算验证了识别机理,表明该传感器可对铁进行定性和定量分析。细胞成像和斑马鱼成像实验进一步证明了该传感器在生物发光成像领域的潜在应用。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/1562/11990252/8599bf8c9227/molecules-30-01579-g001.jpg

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