Safety and efficacy of aneurysms treated with endovascular devices (The SEATED Study).

OBJECTIVES

To create a nationwide consortium to gather all the data related to advanced devices used for aneurysm treatment and conduct pragmatic real-world studies despite the variations among all centres. The strength of this study will be in pooling data of the less commonly used recent devices where there is less evidence. The study will be prospective and retrospective where the initial recruitment figure is expected to be around 5000 patients.

METHODS

To assess how endovascular techniques vary among different UK centres, we illustrate the results of initial surveys that were sent to those centres across the United Kingdom using a single device, the pipeline embolization device with vantage technology (PEDV).

RESULTS

Although the centres were using the same device, the antiplatelet protocol varied from one centre to another as well as follow-up protocols according to the local experience, patient clinical status or even according to the adjuncts uses (e.g., adjunct coiling).

CONCLUSIONS

The illustrated results show that although the centres were using the same device, the antiplatelet protocol varied from one centre to another. Also, follow-up protocols vary from one centre to another according to the local experience, patient clinical status or even according to the adjuncts used (e.g., adjunct coiling). This exemplar serves to illustrate that a nationwide consortium can pool and analyse data of any recent endovascular device.

ADVANCES IN KNOWLEDGE

Obtaining nationwide data regarding safety, efficacy as well as risk factors for aneurysm recurrence when using recent devices. This study will add valuable data regarding the less commonly used recent devices where there is less evidence.