Bassiouny Ahmed R, Sastry Anand, Mortimer Alex, Lynch Jeremy, Sonwalkar Hemant, Bleakley Aaron, Iqbal Ahmed, Narata Ana Paula, Patankar Tufail, Fathallah Islim, Kandasamy Naga, Balasundaram Parthiban, Sciacca Sara, Siddiqui Juveria, Booth Thomas C
School of Biomedical Engineering & Imaging Sciences, King's College London, London, SE1 7EH, United Kingdom.
Diagnostic Radiology, Faculty of Medicine, Mansoura University, Mansoura, 35516, Egypt.
Br J Radiol. 2025 Aug 1;98(1172):1227-1232. doi: 10.1093/bjr/tqaf094.
To create a nationwide consortium to gather all the data related to advanced devices used for aneurysm treatment and conduct pragmatic real-world studies despite the variations among all centres. The strength of this study will be in pooling data of the less commonly used recent devices where there is less evidence. The study will be prospective and retrospective where the initial recruitment figure is expected to be around 5000 patients.
To assess how endovascular techniques vary among different UK centres, we illustrate the results of initial surveys that were sent to those centres across the United Kingdom using a single device, the pipeline embolization device with vantage technology (PEDV).
Although the centres were using the same device, the antiplatelet protocol varied from one centre to another as well as follow-up protocols according to the local experience, patient clinical status or even according to the adjuncts uses (e.g., adjunct coiling).
The illustrated results show that although the centres were using the same device, the antiplatelet protocol varied from one centre to another. Also, follow-up protocols vary from one centre to another according to the local experience, patient clinical status or even according to the adjuncts used (e.g., adjunct coiling). This exemplar serves to illustrate that a nationwide consortium can pool and analyse data of any recent endovascular device.
Obtaining nationwide data regarding safety, efficacy as well as risk factors for aneurysm recurrence when using recent devices. This study will add valuable data regarding the less commonly used recent devices where there is less evidence.
创建一个全国性联盟，收集与用于动脉瘤治疗的先进设备相关的所有数据，并开展务实的真实世界研究，尽管各中心之间存在差异。本研究的优势在于汇总使用证据较少的近期较少使用设备的数据。该研究将兼具前瞻性和回顾性，预计初始招募人数约为5000名患者。
为评估英国不同中心的血管内技术差异，我们展示了使用单一设备——具有优势技术的管道栓塞装置（PEDV）发送给英国各中心的初始调查结果。
尽管各中心使用的是同一设备，但抗血小板方案因中心而异，随访方案也因当地经验、患者临床状况甚至辅助使用情况（如辅助弹簧圈栓塞）而有所不同。
所示结果表明，尽管各中心使用同一设备，但抗血小板方案因中心而异。此外，随访方案也因当地经验、患者临床状况甚至辅助使用情况（如辅助弹簧圈栓塞）而在各中心之间有所不同。这个例子说明全国性联盟可以汇总和分析任何近期血管内设备的数据。
获取有关使用近期设备时动脉瘤复发的安全性、有效性以及风险因素的全国性数据。本研究将为使用证据较少的近期较少使用设备添加有价值的数据。
