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用于生理评估的光电容积脉搏波信号动力学中的结构功能

Structure function in photoplethysmographic signal dynamics for physiological assessment.

作者信息

de Pedro-Carracedo Javier, Fuentes-Jimenez David, Cabrera-Umpiérrez María Fernanda, González-Marcos Ana Pilar

机构信息

Life Supporting Technologies (LifeSTech), ETSI Telecomunicación, Universidad Politécnica de Madrid (UPM), E-28040, Madrid, Spain.

Escuela Politécnica Superior, Departamento de Automática, Universidad de Alcalá (UAH), E-28871, Alcalá de Henares (Madrid), Spain.

出版信息

Sci Rep. 2025 Apr 26;15(1):14645. doi: 10.1038/s41598-025-97573-4.

Abstract

Physiological systems are inherently complex, driven by non-linear interactions among various subsystems that govern their function across diverse spatiotemporal scales. Understanding this interconnectedness is crucial; in this sense, the structure function enables us to dissect the dynamic intricacies of biological responses. By examining amplitude fluctuations across different timescales, we can gain valuable insights into the variability and adaptability of these vital systems. A structure function serves as an essential tool for uncovering long-term correlations that highlight self-organizing behavior. Additionally, it effectively examines the fractal characteristics of short-term signals influenced by the measurement noise often present in biological data. This paper presents a novel investigation into how various parameters of the structure function of the PhotoPlethysmoGraphic (PPG) signal can serve as reliable physiological biomarkers indicative of an individual's cardiorespiratory activity level. Preliminary tests on 40 students from the Universidad Politécnica de Madrid (UPM), all young and healthy individuals aged between 19 and 30, yielded promising results. These findings enhance our understanding of PPG signal dynamics from a physiological standpoint and provide a procedural framework for real-time patient monitoring and health assessment in clinical environments.

摘要

生理系统本质上是复杂的,由各种子系统之间的非线性相互作用驱动,这些子系统在不同的时空尺度上控制着它们的功能。理解这种相互联系至关重要;从这个意义上说,结构函数使我们能够剖析生物反应的动态复杂性。通过检查不同时间尺度上的振幅波动,我们可以深入了解这些重要系统的可变性和适应性。结构函数是揭示突出自组织行为的长期相关性的重要工具。此外,它有效地检验了受生物数据中经常存在的测量噪声影响的短期信号的分形特征。本文对光电容积脉搏波描记(PPG)信号结构函数的各种参数如何作为反映个体心肺活动水平的可靠生理生物标志物进行了新颖的研究。对马德里理工大学(UPM)的40名学生进行的初步测试,这些学生都是年龄在19岁至30岁之间的年轻健康个体,取得了有希望的结果。这些发现从生理学角度增强了我们对PPG信号动态的理解,并为临床环境中的实时患者监测和健康评估提供了一个程序框架。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/a943/12033369/e151b8c60b12/41598_2025_97573_Fig1_HTML.jpg

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