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西班牙裔种族、地理位置及保险状况对接受经皮冠状动脉介入治疗患者心血管结局的影响

Impact of Hispanic Ethnicity, Geography, and Insurance Status on Cardiovascular Outcomes in Patients Undergoing Percutaneous Coronary Intervention.

作者信息

Sampath-Kumar Revathy, Mahmud Ehtisham, Palakodeti Vachaspathi, Ang Lawrence, Al Khiami Belal, Melendez Anna, Reeves Ryan, Ben-Yehuda Ori

机构信息

Division of Cardiovascular Medicine, University of California-San Diego, San Diego, California, USA.

Division of Cardiovascular Medicine, University of California-San Diego, San Diego, California, USA.

出版信息

JACC Adv. 2025 Apr 26;4(5):101723. doi: 10.1016/j.jacadv.2025.101723.

Abstract

BACKGROUND

Hispanics are the largest and fastest growing ethnic minority population in the United States yet are poorly represented in cardiovascular outcomes studies. UC San Diego Health is a primary percutaneous coronary intervention (PCI) center for a diverse group of patients given its proximity to Mexico and underserved rural southeast Imperial County.

OBJECTIVES

The purpose of this study was to study the association between Hispanic ethnicity, geography, insurance status, and PCI outcomes.

METHODS

The UC San Diego Health internal National Cardiovascular Data Registry CathPCI Registry was used to obtain data on patients who underwent PCI from January 2007 to September 2022. Complications and all-cause mortality within 1-year post-PCI were assessed.

RESULTS

A total of 8,295 patients (age 66 years [IQR: 58-75 years], 72% male, 33% Hispanic ethnicity, and 30% from Imperial County) were included. Hispanics and patients from Imperial County irrespective of race or ethnicity had higher body mass index and were more likely to have diabetes, hypertension, hyperlipidemia, end-stage renal disease, and peripheral vascular disease. There was no difference in mortality rates between Hispanic and non-Hispanic Whites in the entire population. However, within Imperial County, Hispanics had significantly higher 30-day (1.4% vs 0.3% P = 0.02), 6-month (2.2% vs 0.8% P = 0.01), and 1-year (2.9% vs 0.9% P = 0.004) mortality rates compared to non-Hispanic Whites. Patients in Imperial County had lower 30-day (1.2% vs 1.9% P = 0.01), 6-month (1.9% vs 3.3% P < 0.001), and 1-year (2.4% vs 5% P < 0.001) mortality rates compared to patients outside of Imperial County. There was no difference in all-cause mortality rates by insurance status in non-Hispanic Whites. Uninsured Hispanic patients had a higher 30-day mortality rate compared to Hispanic patients who had Medicare/Medicaid or private insurance (4.5% vs 2.0% vs 1.0% P = 0.005). Within Imperial County, uninsured Hispanic patients had markedly higher 30-day mortality rate compared to Hispanic patients who had Medicare/Medicaid or private insurance (10.4% vs 1.6% vs 0.3% P < 0.001).

CONCLUSIONS

In socioeconomically disadvantaged areas, Hispanic patients had worse outcomes compared to non-Hispanic Whites compounded by uninsured status. There are complex demographic disparities in PCI outcomes for Hispanic patients and those residing in border zones which need to be recognized and mitigated.

摘要

背景

西班牙裔是美国最大且增长最快的少数族裔群体,但在心血管疾病结局研究中的代表性不足。鉴于加州大学圣地亚哥分校医疗中心靠近墨西哥且地处帝国县东南部农村地区,医疗服务匮乏,因此它是一个为不同患者群体提供主要经皮冠状动脉介入治疗(PCI)的中心。

目的

本研究旨在探讨西班牙裔种族、地理位置、保险状况与PCI结局之间的关联。

方法

利用加州大学圣地亚哥分校医疗中心内部的国家心血管数据注册中心导管PCI注册数据,获取2007年1月至2022年9月期间接受PCI治疗的患者数据。评估PCI术后1年内的并发症和全因死亡率。

结果

共纳入8295例患者(年龄66岁[四分位间距:58 - 75岁],72%为男性,33%为西班牙裔,30%来自帝国县)。西班牙裔患者以及来自帝国县的患者,无论种族如何,体重指数均较高,且更易患糖尿病、高血压、高脂血症、终末期肾病和外周血管疾病。在整个人口中,西班牙裔和非西班牙裔白人的死亡率无差异。然而,在帝国县内,与非西班牙裔白人相比,西班牙裔患者的30天死亡率(1.4%对0.3%,P = 0.02)、6个月死亡率(2.2%对0.8%,P = 0.01)和1年死亡率(2.9%对0.9%,P = 0.004)显著更高。与帝国县以外的患者相比,帝国县内的患者30天死亡率(1.2%对1.9%,P = 0.01)、6个月死亡率(1.9%对3.3%,P < 0.001)和1年死亡率(2.4%对5%,P < 0.001)更低。非西班牙裔白人的全因死亡率在保险状况方面无差异。未参保的西班牙裔患者的30天死亡率高于有医疗保险/医疗补助或私人保险的西班牙裔患者(4.5%对2.0%对1.0%,P = 0.005)。在帝国县内,未参保的西班牙裔患者的30天死亡率明显高于有医疗保险/医疗补助或私人保险的西班牙裔患者(10.4%对1.6%对0.3%,P < 0.001)。

结论

在社会经济处于不利地位的地区,与非西班牙裔白人相比,西班牙裔患者结局更差,未参保状况使其雪上加霜。西班牙裔患者以及居住在边境地区的患者在PCI结局方面存在复杂的人口统计学差异,需要予以认识和缓解。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/bdf5/12059334/d3204b4bad6d/ga1.jpg

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