Morais Liliana Patricia Ferreira, Moore Zena Elizabeth Helen, Patton Declan, Connor Tom O', Avsar Pinar, Wilson Hannah Jane Elizabeth
Royal College of Surgeons in Ireland (RCSI), University of Medicine and Health Sciences, Dublin, Ireland.
School of Nursing and Midwifery, RCSI University of Medicine and Health Sciences, Dublin, Ireland.
Int Wound J. 2025 May;22(5):e70194. doi: 10.1111/iwj.70194.
This systematic review aimed to determine the impact of negative pressure wound therapy on healing in patients with pilonidal sinus following surgical excision. Using systematic review methodology, we included original research studies written in English. The search was conducted using CINAHL Plus, Ovid, PubMed, EBSCO Host and Cochrane databases. Quality appraisal was undertaken using the Cochrane Collaboration tool for assessing risk of bias and the Grading of Recommendations Assessment, Development and Evaluation (GRADE). Data were analysed using meta-analysis where appropriate; otherwise, the data are presented narratively. Ten studies were included with a mean sample size of 61 (SD: 33). Three studies were randomised control trials, four were retrospective studies, two were prospective cohort studies and one was pre-post study. Studies showed reduction in healing time, recurrence rates and postoperative pain, as well as higher patients' satisfaction with the use negative pressure wound therapy, however, the certainty of the evidence was very low. The evidence for the intervention is uncertain thus, it is unclear whether NPWT makes any difference when compared to any other dressings, on time to healing, recurrence, pain or patient's experience. Further high-quality research with larger sample sizes is recommended to clearly explore the impact of NPWT on PS healing, recurrence, pain and patient's satisfaction.
本系统评价旨在确定负压伤口治疗对藏毛窦患者手术切除后愈合的影响。采用系统评价方法，我们纳入了英文撰写的原始研究。检索使用CINAHL Plus、Ovid、PubMed、EBSCO Host和Cochrane数据库进行。使用Cochrane协作网评估偏倚风险的工具以及推荐分级评估、制定和评价（GRADE）进行质量评估。在适当情况下使用荟萃分析对数据进行分析；否则，以叙述方式呈现数据。纳入了10项研究，平均样本量为61（标准差：33）。3项研究为随机对照试验，4项为回顾性研究，2项为前瞻性队列研究，1项为前后对照研究。研究表明，使用负压伤口治疗可缩短愈合时间、降低复发率和术后疼痛，患者满意度也更高，然而，证据的确定性非常低。该干预措施的证据尚不确定，因此，与其他任何敷料相比，负压伤口治疗在愈合时间、复发、疼痛或患者体验方面是否有任何差异尚不清楚。建议开展进一步的大样本高质量研究，以明确探讨负压伤口治疗对藏毛窦愈合、复发、疼痛和患者满意度的影响。
