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来自髂嵴的距骨骨膜周围植骨术(TOPIC):距骨外侧大型骨软骨损伤的2年前瞻性研究结果

Talar OsteoPeriostic Grafting From the Iliac Crest (TOPIC): Prospective 2-Year Outcomes for Large Lateral Osteochondral Lesions of the Talus.

作者信息

Hollander Julian J, Emanuel Kaj S, Dahmen Jari, Kerkhoffs Gino M M J, Stufkens Sjoerd A S

机构信息

Department of Orthopaedic Surgery and Sports Medicine, Amsterdam UMC, Location AMC, University of Amsterdam, Amsterdam, the Netherlands.

Amsterdam Movement Sciences, Programs Sports and Musculoskeletal Health, Amsterdam, the Netherlands.

出版信息

Foot Ankle Int. 2025 Jun;46(6):580-586. doi: 10.1177/10711007251329033. Epub 2025 Apr 27.

Abstract

BACKGROUND

The results of the Talar OsteoPeriostic grafting from the Iliac Crest (TOPIC) procedure for lateral osteochondral lesions of the talus (OLTs) are unknown. Therefore, the present prospective study aims to assess the numeric rating scale (NRS) of pain during walking at 2-year follow-up. Secondarily, the aim is to assess other clinical, radiologic, and safety outcomes.

METHODS

This is a single-center, nonrandomized prospective cohort study in which all press-fit lateral TOPIC patients for an OLT are included. Patients with a follow-up of at least 2 years without a concomitant osteochondral lesion of the tibial plafond were included. The primary outcome is the NRS of pain during walking. Secondary clinical outcomes included the NRS during rest and during stair climbing. Additionally, the Foot and Ankle Outcome Score (FAOS), the AOFAS ankle-hindfoot score, and the mental and physical component summary of the 36-Item Short Form Health Survey were recorded. Radiologic follow-up was performed using computed tomography (CT) scans.

RESULTS

After application of the inclusion and exclusion criteria, 7 patients were included in the present study. The median age at time of surgery was 31.1 years. The NRS of pain during walking improved from a median of 5 (4-7) preoperatively to 1 (0-1) at 2 years of follow-up ( = .02). All FAOS subscales improved significantly, except the FAOS symptoms subscale. Graft consolidation was observed in 100% of the patients and cysts were present in 5 of 6 patients. No complications occurred and no patients complained of donor site morbidity. No reoperations were performed.

CONCLUSION

In the first 7 prospectively followed patients who underwent the TOPIC procedure for large osteochondral lesions of the lateral talar dome, an improvement of the NRS of pain during walking from median 5 preoperatively to 1 at 2-year follow-up was observed.

摘要

背景

距骨外侧骨软骨损伤(OLT)的取自髂嵴的距骨骨膜周围移植术(TOPIC)的结果尚不清楚。因此,本前瞻性研究旨在评估2年随访时步行时疼痛的数字评分量表(NRS)。其次,目的是评估其他临床、放射学和安全性结果。

方法

这是一项单中心、非随机前瞻性队列研究,纳入了所有接受OLT压配式外侧TOPIC手术的患者。纳入随访至少2年且无胫骨平台合并骨软骨损伤的患者。主要结局是步行时疼痛的NRS。次要临床结局包括休息时和爬楼梯时的NRS。此外,记录足踝结局评分(FAOS)、美国足踝外科协会(AOFAS)踝后足评分以及36项简明健康调查的心理和身体成分总结。使用计算机断层扫描(CT)进行放射学随访。

结果

应用纳入和排除标准后,本研究纳入了7例患者。手术时的中位年龄为31.1岁。步行时疼痛的NRS从术前的中位数5(4-7)改善至随访2年时的1(0-1)(P = 0.02)。除FAOS症状子量表外,所有FAOS子量表均显著改善。100%的患者观察到植骨融合,6例患者中有5例存在囊肿。未发生并发症,无患者主诉供区并发症。未进行再次手术。

结论

在首批7例接受TOPIC手术治疗外侧距骨穹窿大骨软骨损伤的前瞻性随访患者中,观察到步行时疼痛的NRS从术前中位数5改善至随访2年时的1。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/f078/12145484/3c8996cda29b/10.1177_10711007251329033-fig1.jpg

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