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尿液培养中的抗抑郁药与抗生素耐药性:一项队列研究。

Antidepressants and antibiotic resistance in urine cultures: a cohort study.

作者信息

Sears Isaac, Davis Michel, Gibas Kevin, Mermel Leonard, Heffernan Daithi S

机构信息

The Warren Alpert Medical School of Brown University, Providence, RI, USA.

Department of Medicine, The Warren Alpert Medical School of Brown University, Providence, RI, USA.

出版信息

Antimicrob Steward Healthc Epidemiol. 2025 Apr 23;5(1):e98. doi: 10.1017/ash.2025.73. eCollection 2025.

Abstract

evidence of antidepressant-driven antibiotic resistance has recently been described. In this retrospective cohort study, significant associations are identified between antidepressant use and antibiotic resistance on urine cultures taken in the Emergency Department. This epidemiologic data supports previous  work and raises additional questions for further study.

摘要

最近有关于抗抑郁药导致抗生素耐药性的证据被描述。在这项回顾性队列研究中,在急诊科采集的尿培养样本中,发现抗抑郁药的使用与抗生素耐药性之间存在显著关联。这一流行病学数据支持了之前的研究工作,并提出了更多有待进一步研究的问题。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/c444/12022929/ff8fd3a56a94/S2732494X25000737_fig1.jpg

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