Huang Lu, Liu Xin, Yi Jiang, Jiao Yu-Wei, Zhang Tian-Qi, Zhu Guang-Yao, Yu Shu-Yue, Liu Zhong-Liang, Gao Min, Duan Xiao-Qin
School of Nursing, Jilin University, Changchun, China.
Department of Rehabilitation, The Second Hospital of Jilin University, Changchun, China.
Front Aging Neurosci. 2025 Apr 11;17:1503672. doi: 10.3389/fnagi.2025.1503672. eCollection 2025.
This study proposes to construct a model to replace the on-road test and provide a bundled assessment on the driving function of stroke patients.
Clinical data were collected from 38 stroke patients who specified meeting criteria. Bundled assessment including the Oxford Cognitive Screen (OCS) scale ratings, eye tracking data obtained under the same eight simulated driving tasks as in subject 3, Fugl-Meyer Assessment-lower extremity (FMA-LE) scores, lower limb ankle muscle strength and active range of motion (AROM), and performance on the simulated driving machine. All patients were transported to a driving school and underwent the on-road test. The subject was classified as either Success or Unsuccess group according to whether they had completed the on-road test. A random forest algorithm was then applied to construct a binary classification model based on the data obtained from the two groups.
Compared to the Unsuccess group, the Success group had higher scores on the OCS scale for "crossing out the intact heart" ( = 0.015) and lower scores for "executive function" ( = 0.009). The analysis of eye tracking recordings revealed that the Success group exhibited a reduced pupil change rate, a higher proportion of eye movement types that were fixations, a longer mean fixation duration, and a significantly faster mean average velocity of saccade in the U-turn ( = 0.032), Left-turn ( = 0.015), and Free-driving tasks ( = 0.027). Compared to the Unsuccess group, the Success group had higher FMA-LE scores ( = 0.018), higher manual muscle strength for ankle dorsiflexion ( = 0.024) and plantarflexion ( = 0.040), and greater AROM in dorsiflexion ( = 0.020) and plantarflexion ( = 0.034). The success group demonstrated fewer collisions ( < 0.001), lane violations ( < 0.001), and incorrect maneuvers ( < 0.001) when completing the simulated driving task. The random forest model for bundled assessment demonstrated an accuracy of > 83% based on 56 statistically distinct input data sets.
The bundled assessment, which includes cognitive, eye tracking, motor, and simulated driver performance, offers a potential indicator of whether stroke patients may be able to pass the on-road test. Furthermore, the established random forest classification model has demonstrated efficacy in predicting on-road test outcomes, which is worthy of further clinical application.
本研究旨在构建一个模型,以取代道路测试,并对中风患者的驾驶功能进行综合评估。
收集了38例符合特定标准的中风患者的临床数据。综合评估包括牛津认知筛查(OCS)量表评分、在与受试者3相同的八项模拟驾驶任务下获得的眼动追踪数据、Fugl-Meyer下肢评估(FMA-LE)评分、下肢踝关节肌肉力量和主动活动范围(AROM)以及模拟驾驶机器上的表现。所有患者均被送往驾校并接受道路测试。根据受试者是否完成道路测试,将其分为成功组或失败组。然后应用随机森林算法,基于两组获得的数据构建二元分类模型。
与失败组相比,成功组在OCS量表中“划掉完整心脏”的得分更高( = 0.015),而“执行功能”的得分更低( = 0.009)。眼动追踪记录分析显示,成功组在掉头( = 0.032)、左转( = 0.015)和自由驾驶任务( = 0.027)中瞳孔变化率降低、注视类型的眼动比例更高、平均注视持续时间更长,且扫视的平均速度明显更快。与失败组相比,成功组的FMA-LE评分更高( = 0.018),踝关节背屈( = 0.024)和跖屈( = 0.040)的手动肌力更高,背屈( = 0.020)和跖屈( = 0.034)的AROM更大。成功组在完成模拟驾驶任务时碰撞次数更少( < 0.001)、车道违规次数更少( < 0.001)且错误操作更少( < 0.001)。基于56个统计上不同的输入数据集,综合评估的随机森林模型准确率超过83%。
包括认知、眼动追踪、运动和模拟驾驶表现的综合评估,为中风患者是否能够通过道路测试提供了一个潜在指标。此外,所建立的随机森林分类模型在预测道路测试结果方面已显示出有效性,值得进一步临床应用。