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吲哚菁绿荧光成像技术在直肠癌腹腔镜手术中的进展

Advancement of indocyanine green fluorescence imaging technology in laparoscopic surgery for rectal cancer.

作者信息

Wu Chu-Ying, Zhu Yue-Jia, Ye Kai

机构信息

Department of Colorectal Surgery, The Second Affiliated Hospital of Fujian Medical University, Quanzhou 362000, Fujian Province, China.

出版信息

World J Gastrointest Surg. 2025 Apr 27;17(4):104020. doi: 10.4240/wjgs.v17.i4.104020.

DOI:10.4240/wjgs.v17.i4.104020
PMID:40291865
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC12019059/
Abstract

Indocyanine green fluorescence imaging technology has been increasingly utilized in rectal surgery in recent years. As a safe tracer, indocyanine green can facilitate lymph node tracing, assess the blood supply at anastomotic sites, and localize tumour lesions during laparoscopic surgery, thereby resulting in favourable outcomes. This technology helps surgeons to achieve more precise diagnoses and treatments in laparoscopic procedures, thus ultimately benefiting patients. However, the current application of indocyanine green fluorescence imaging technology still lacks standardized regulations, and certain effects remain contentious. This study provides a comprehensive review of the application of indocyanine green in laparoscopic surgery for rectal cancer based on the pertinent literature.

摘要

近年来,吲哚菁绿荧光成像技术在直肠手术中的应用越来越广泛。作为一种安全的示踪剂,吲哚菁绿有助于在腹腔镜手术中进行淋巴结示踪、评估吻合口血供以及定位肿瘤病变,从而产生良好的效果。这项技术有助于外科医生在腹腔镜手术中实现更精确的诊断和治疗,最终使患者受益。然而,目前吲哚菁绿荧光成像技术的应用仍缺乏标准化规范,某些效果仍存在争议。本研究基于相关文献对吲哚菁绿在腹腔镜直肠癌手术中的应用进行了全面综述。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/b759/12019059/77f670152e80/104020-g002.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/b759/12019059/7888392b73f3/104020-g001.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/b759/12019059/77f670152e80/104020-g002.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/b759/12019059/7888392b73f3/104020-g001.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/b759/12019059/77f670152e80/104020-g002.jpg

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1
Advancement of indocyanine green fluorescence imaging technology in laparoscopic surgery for rectal cancer.吲哚菁绿荧光成像技术在直肠癌腹腔镜手术中的进展
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本文引用的文献

1
Robotic Lateral Pelvic Lymph Node Dissection in Rectal Cancer: A Feasibility Study from a European Centre.机器人辅助直肠癌侧方盆腔淋巴结清扫术:来自欧洲某中心的可行性研究
J Clin Med. 2023 Dec 23;13(1):90. doi: 10.3390/jcm13010090.
2
Clinical application of machine learning and computer vision to indocyanine green quantification for dynamic intraoperative tissue characterisation: how to do it.机器学习和计算机视觉在吲哚菁绿定量动态术中组织特征化中的临床应用:如何实现。
Surg Endosc. 2023 Aug;37(8):6361-6370. doi: 10.1007/s00464-023-09963-2. Epub 2023 Mar 9.
3
Lateral pelvic lymph node metastasis in T2 low rectal cancer: is TME alone sufficient for cure?
T2 低位直肠癌的侧方盆淋巴结转移:TME 单独治疗是否足以治愈?
Jpn J Clin Oncol. 2023 Apr 29;53(5):386-392. doi: 10.1093/jjco/hyad008.
4
Establishing and validating predictive nomograms for lateral pelvic lymph node metastasis in patients with rectal cancer based on radiologic factors and clinicopathologic characteristics.基于放射学因素和临床病理特征建立并验证直肠癌患者侧方盆腔淋巴结转移的预测列线图。
Eur J Surg Oncol. 2023 Apr;49(4):747-754. doi: 10.1016/j.ejso.2022.12.014. Epub 2022 Dec 29.
5
Short-term outcomes of near-infrared imaging using indocyanine green in laparoscopic lateral pelvic lymph node dissection for middle-lower rectal cancer: A propensity score-matched cohort analysis.吲哚菁绿近红外成像在腹腔镜中下直肠癌侧方盆腔淋巴结清扫术中的短期结局:一项倾向评分匹配队列分析
Front Med (Lausanne). 2022 Nov 10;9:1039928. doi: 10.3389/fmed.2022.1039928. eCollection 2022.
6
Detection of Colorectal Liver Metastases Using Near-Infrared Fluorescence Imaging During Hepatectomy: Prospective Single Centre UK Study.利用肝切除术中近红外荧光成像检测结直肠癌肝转移:英国单中心前瞻性研究。
J Gastrointest Cancer. 2023 Jun;54(2):574-579. doi: 10.1007/s12029-022-00836-w. Epub 2022 May 26.
7
Prognostic significance of lateral pelvic lymph node dissection for middle-low rectal cancer patients with lateral pelvic lymph node metastasis: a propensity score matching study.中低位直肠癌合并侧方淋巴结转移患者行侧方盆壁淋巴结清扫术的预后意义:倾向评分匹配研究。
BMC Cancer. 2022 Feb 3;22(1):136. doi: 10.1186/s12885-022-09254-4.
8
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Dis Colon Rectum. 2022 Mar 1;65(3):314-321. doi: 10.1097/DCR.0000000000002246.
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Dis Colon Rectum. 2021 Aug 1;64(8):995-1002. doi: 10.1097/DCR.0000000000002007.
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J Laparoendosc Adv Surg Tech A. 2021 May;31(5):517-523. doi: 10.1089/lap.2020.0895. Epub 2021 Mar 2.