Jeon Youngjin, Kim Minji, Song Kwang Hoon
Department of Nano-Bioengineering, Incheon National University, 119, Academy-ro, Yeonsu-gu, Incheon 22012, Republic of Korea.
Research Center of Brain-Machine Interface, Incheon National University, 119, Academy-ro, Yeonsu-gu, Incheon 22012, Republic of Korea.
Polymers (Basel). 2025 Mar 14;17(6):765. doi: 10.3390/polym17060765.
The architectures of hydrogels fabricated with stereolithography (SLA) 3D printing systems have played various roles in bioengineering applications. Typically, the SLA systems successively illuminated light to a layer of photo-crosslinkable hydrogel precursors for the fabrication of hydrogels. These SLA systems can be classified into point-scanning types and digital micromirror device (DMD) types. The point-scanning types form layers of hydrogels by scanning the precursors with a focused light, while DMD types illuminate 2D light patterns to the precursors to form each hydrogel layer at once. Overall, SLA systems were cost-effective and allowed the fabrication of hydrogels with good shape fidelity and uniform mechanical properties. As a result, hydrogel constructs fabricated with the SLA 3D printing systems were used to regenerate tissues and develop lab-on-a-chip devices and native tissue-like models.
利用立体光刻(SLA)3D打印系统制造的水凝胶结构在生物工程应用中发挥了多种作用。通常,SLA系统依次将光照射到一层可光交联的水凝胶前体上以制造水凝胶。这些SLA系统可分为点扫描型和数字微镜器件(DMD)型。点扫描型通过用聚焦光扫描前体来形成水凝胶层,而DMD型则将二维光图案照射到前体上以一次性形成每个水凝胶层。总体而言,SLA系统具有成本效益,能够制造出形状保真度高且机械性能均匀的水凝胶。因此,用SLA 3D打印系统制造的水凝胶构建体被用于组织再生、开发芯片实验室设备和天然组织样模型。