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1990年至2021年育龄女性胰腺炎的全球发病率和死亡率。

Global incidence and mortality of pancreatitis in women of childbearing age from 1990 to 2021.

作者信息

Jiang Wenkai, He Ru, Sun Huiqi, Zhao Tianxin, Liu Xinru, Zhou Wence

机构信息

The Second Clinical Medical School, Lanzhou University, No. 222 Tianshui Road (South), Cheng-Guan District, Lanzhou City, 730030, China.

Department of General Surgery, The First Affiliated Hospital of Xi'an Medical University, Xi'an, 710077, China.

出版信息

Sci Rep. 2025 Apr 28;15(1):14753. doi: 10.1038/s41598-025-99435-5.

Abstract

To analyze the global burden of pancreatitis in women of childbearing age (WCBA) at the global, regional and national levels from 1990 to 2021. Data for pancreatitis incidence and deaths in females aged 15 to 49 years were downloaded from the Global Burden of Disease 2021 database. Estimated annual percentage changes (EAPCs) were calculated to describe the temporal trends. In 2021, the global numbers of incident cases and deaths of pancreatitis in the WCBA were 505,012 (409,536 to 627,684) and 7,002 (5,647 to 8,857), respectively. From 1990 to 2021, the global incidence and death rates of pancreatitis in the WCBA showed downward trends, with EAPCs of -0.15 (-0.21 to -0.09) and - 0.42 (-0.58 to -0.26), respectively. The most significant decreases in incidence and death rates were observed among females aged 40 to 44 years. Eastern Europe had the highest incidence and death rates in 2021. Countries with high socio-demographic index (SDI) showed the highest incidence rate, while showed greatest decrease in incidence during the past 32 years. The global pancreatitis incidence and death in WCBA has decreased since 1990, but the incidence is still high in countries with high-SDI. More efficient public health measures are needed to reduce the burden of pancreatitis.

摘要

分析1990年至2021年全球、区域和国家层面育龄期女性胰腺炎的全球负担。从全球疾病负担2021数据库下载15至49岁女性胰腺炎发病率和死亡数据。计算估计年百分比变化(EAPCs)以描述时间趋势。2021年,育龄期女性胰腺炎的全球发病例数和死亡数分别为505,012例(409,536至627,684例)和7,002例(5,647至8,857例)。1990年至2021年,育龄期女性胰腺炎的全球发病率和死亡率呈下降趋势,EAPCs分别为-0.15(-0.21至-0.09)和-0.42(-0.58至-0.26)。40至44岁女性的发病率和死亡率下降最为显著。2021年,东欧的发病率和死亡率最高。社会人口指数(SDI)高的国家发病率最高,而在过去32年中发病率下降幅度最大。自1990年以来,育龄期女性胰腺炎的全球发病率和死亡率有所下降,但SDI高的国家发病率仍然很高。需要更有效的公共卫生措施来减轻胰腺炎负担。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/a0d0/12038009/8fa13666ee01/41598_2025_99435_Fig1_HTML.jpg

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