奇特的亲属：神秘的树-荆门病毒和正黄病毒属病毒
Strange relatives: the enigmatic arbo-jingmenviruses and orthoflaviviruses.
作者信息
Ogola Edwin O, Roy Amitava, Wollenberg Kurt, Ochwoto Missiani, Bloom Marshall E
机构信息
Biology of Vector Borne Viruses Section, Laboratory of Virology, Rocky Mountain Laboratories, NIAID, NIH, 903 South 4th Street, Hamilton, MT, 59840, USA.
Department of Biomedical and Pharmaceutical Sciences, University of Montana, 32 Campus Drive, Missoula, MT, 59812, USA.
出版信息
Npj Viruses. 2025 Apr 4;3(1):24. doi: 10.1038/s44298-025-00106-z.
Arthropod - and vertebrate-associated jingmenviruses (arbo-JMV) have segmented positive-strand RNA genomes and are provisional members of the genus Orthoflavivirus (family Flaviviridae). Current investigations have described arbo-JMV infection in vertebrate hosts in proximity to humans. This raises concerns about the virus host range and public health implications. This review explores the genomic and evolutionary relationship between arbo-JMV and orthoflaviviruses and evaluates the potential of arbo-JMV to pose a public health threat.
与节肢动物和脊椎动物相关的荆门病毒（虫媒荆门病毒，arbo-JMV）具有分段的正链RNA基因组，是黄病毒属（黄病毒科）的暂定成员。目前的研究已经描述了在靠近人类的脊椎动物宿主中存在虫媒荆门病毒感染。这引发了对该病毒宿主范围及公共卫生影响的担忧。本综述探讨了虫媒荆门病毒与黄病毒之间的基因组和进化关系，并评估了虫媒荆门病毒对公共卫生构成威胁的可能性。
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