McCready Taylor M, Cohen Ethan M, Laynor Gregory, Chebli Perla, Liang Peter S, Renson Audrey
Department of Population Health, New York University Grossman School of Medicine, New York, New York, United States of America.
Section of Internal Medicine, West Virginia University, West Virginia, West Virginia, United States of America.
PLoS One. 2025 Apr 29;20(4):e0322038. doi: 10.1371/journal.pone.0322038. eCollection 2025.
Colorectal cancer (CRC) screening rates are lower among immigrant populations in the United States (US) than the general population. Immigrant communities face structural barriers that disincentivize their engagement from CRC screening. A growing body of literature has evaluated the effects of interventions aimed at increasing CRC screening engagement among various immigrant groups, but there has not yet been a systematic synthesis of this literature.
This review will systematically evaluate quantitative studies assessing the effects of interventions designed to increase CRC screening rates among immigrant populations residing in the US.
We will conduct a comprehensive search of English language peer-reviewed and grey literature using specific keywords and database-specific structured vocabulary on interventions to improve CRC screening rates among immigrants published in 7 databases (PubMed, Cochrane Library (Wiley), CINAHL (EBSCO), ClinicalTrials.gov, Embase (Ovid), Scopus (Elsevier), and Web of Science) from January 1, 2000 to December 31, 2024. All studies will be imported into Covidence. Two reviewers will independently screen titles, abstracts, and full-texts for inclusion and exclusion criteria. Pilot screenings and consensus discussions will ensure accuracy and agreement in study selection and data extraction. Iterative data extraction of eligible studies will include critical appraisal using the Risk of Bias 2 (ROB2) for randomized controlled trials, while other study designs will be appraised with the risk of bias in nonrandomized studies of interventions (ROBINS-I) tool. Data synthesis will disaggregate pooled effect estimates by ethnicity, to the extent possible. The study protocol was pre-registered in International Prospective Register of Systematic reviews (PROSPERO): CRD42023488183.
This systematic review aims to generate an exhaustive summary of the evidence base, including a description of the intervention methods and settings, target populations, recruitment and retention strategies, partnerships and collaborations, and reported outcomes. The results will provide actionable recommendations for public health practitioners, healthcare providers, and policymakers developing tailored interventions and policies aimed at improving CRC screening uptake among diverse immigrant populations in the US.
在美国，移民人群的结直肠癌（CRC）筛查率低于普通人群。移民社区面临一些结构性障碍，这些障碍阻碍了他们参与CRC筛查。越来越多的文献评估了旨在提高不同移民群体CRC筛查参与度的干预措施的效果，但尚未对这些文献进行系统的综合分析。
本综述将系统评估定量研究，这些研究评估了旨在提高居住在美国的移民人群CRC筛查率的干预措施的效果。
我们将使用特定关键词和特定数据库的结构化词汇，对7个数据库（PubMed、Cochrane图书馆（Wiley）、CINAHL（EBSCO）、ClinicalTrials.gov、Embase（Ovid）、Scopus（Elsevier）和Web of Science）中2000年1月1日至2024年12月31日发表的关于提高移民CRC筛查率的干预措施的英文同行评审文献和灰色文献进行全面检索。所有研究将导入Covidence。两名评审员将独立筛选标题、摘要和全文，以确定纳入和排除标准。预筛查和共识讨论将确保在研究选择和数据提取方面的准确性和一致性。对符合条件的研究进行迭代数据提取，包括对随机对照试验使用偏倚风险2（ROB2）进行关键评估，而其他研究设计将使用干预性非随机研究中的偏倚风险（ROBINS-I）工具进行评估。数据合成将尽可能按种族对合并效应估计值进行分解。该研究方案已在国际系统评价前瞻性注册库（PROSPERO）中预先注册：CRD42023488183。
本系统综述旨在生成一份详尽的证据基础总结，包括对干预方法和环境、目标人群、招募和保留策略、伙伴关系与合作以及报告结果的描述。结果将为公共卫生从业者、医疗保健提供者和政策制定者提供可行的建议，以制定针对性的干预措施和政策，旨在提高美国不同移民人群的CRC筛查接受率。
