创伤弧菌在缺乏血清调理素的情况下可抵抗吞噬作用。
Vibrio vulnificus resists phagocytosis in the absence of serum opsonins.
作者信息
Tamplin M L, Specter S, Rodrick G E, Friedman H
出版信息
Infect Immun. 1985 Sep;49(3):715-8. doi: 10.1128/iai.49.3.715-718.1985.
Abstract
Invasive disease caused by Vibrio vulnificus may result partially from resistance to phagocytic host defense mechanisms. The present studies show that V. vulnificus resists phagocytosis by murine peritoneal macrophages in the absence of serum opsonins and extracellular bacterial products, apparently through the anti-phagocytic properties of the bacterial surface.
摘要
创伤弧菌引起的侵袭性疾病可能部分源于对宿主吞噬防御机制的抗性。目前的研究表明，在没有血清调理素和细胞外细菌产物的情况下，创伤弧菌可抵抗小鼠腹膜巨噬细胞的吞噬作用，这显然是通过细菌表面的抗吞噬特性实现的。
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