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创伤弧菌在缺乏血清调理素的情况下可抵抗吞噬作用。

Vibrio vulnificus resists phagocytosis in the absence of serum opsonins.

作者信息

Tamplin M L, Specter S, Rodrick G E, Friedman H

出版信息

Infect Immun. 1985 Sep;49(3):715-8. doi: 10.1128/iai.49.3.715-718.1985.

DOI:10.1128/iai.49.3.715-718.1985
PMID:4030101
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC261253/
Abstract

Invasive disease caused by Vibrio vulnificus may result partially from resistance to phagocytic host defense mechanisms. The present studies show that V. vulnificus resists phagocytosis by murine peritoneal macrophages in the absence of serum opsonins and extracellular bacterial products, apparently through the anti-phagocytic properties of the bacterial surface.

摘要

创伤弧菌引起的侵袭性疾病可能部分源于对宿主吞噬防御机制的抗性。目前的研究表明，在没有血清调理素和细胞外细菌产物的情况下，创伤弧菌可抵抗小鼠腹膜巨噬细胞的吞噬作用，这显然是通过细菌表面的抗吞噬特性实现的。

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Vibrio vulnificus resists phagocytosis in the absence of serum opsonins.创伤弧菌在缺乏血清调理素的情况下可抵抗吞噬作用。
Infect Immun. 1985 Sep;49(3):715-8. doi: 10.1128/iai.49.3.715-718.1985.
2
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本文引用的文献

1
Role of iron in the pathogenesis of Vibrio vulnificus infections.铁在创伤弧菌感染发病机制中的作用。
Infect Immun. 1981 Nov;34(2):503-7. doi: 10.1128/iai.34.2.503-507.1981.
2
Interaction of Vibrio vulnificus with human polymorphonuclear leukocytes: association of virulence with resistance to phagocytosis.创伤弧菌与人类多形核白细胞的相互作用：毒力与抗吞噬作用的关联。
J Infect Dis. 1981 Sep;144(3):244-8. doi: 10.1093/infdis/144.3.244.
3
Edema and hemoconcentration in mice experimentally infected with Vibrio vulnificus.实验感染创伤弧菌的小鼠出现水肿和血液浓缩。
Infect Immun. 1981 Jun;32(3):1193-9. doi: 10.1128/iai.32.3.1193-1199.1981.
4
Inhibition of yeast phagocytosis and cell spreading by glucocorticoids in cultures of resident murine peritoneal macrophages.糖皮质激素对驻留小鼠腹腔巨噬细胞培养物中酵母吞噬作用和细胞铺展的抑制作用。
J Immunopharmacol. 1981;3(2):171-92. doi: 10.3109/08923978109026425.
5
Detection of extracellular toxin(s) produced by Vibrio vulnificus.创伤弧菌产生的细胞外毒素的检测
Infect Immun. 1981 Aug;33(2):583-90. doi: 10.1128/iai.33.2.583-590.1981.
6
Diseases of humans (other than cholera) caused by vibrios.由弧菌引起的人类疾病（霍乱除外）。
Annu Rev Microbiol. 1980;34:341-67. doi: 10.1146/annurev.mi.34.100180.002013.
7
Influence of the Escherichia coli capsule on complement fixation and on phagocytosis and killing by human phagocytes.大肠杆菌荚膜对补体结合以及对人类吞噬细胞吞噬和杀伤作用的影响。
J Clin Invest. 1980 Jan;65(1):82-94. doi: 10.1172/JCI109663.
8
Vibrio vulnificus (lactose-positive vibrio) and Vibrio parahaemolyticus differ in their susceptibilities to human serum.创伤弧菌（乳糖阳性弧菌）和副溶血性弧菌对人血清的敏感性不同。
Infect Immun. 1981 May;32(2):964-6. doi: 10.1128/iai.32.2.964-966.1981.
9
Extracellular phospholipase A2 and lysophospholipase produced by Vibrio vulnificus.创伤弧菌产生的细胞外磷脂酶A2和溶血磷脂酶。
Infect Immun. 1984 Aug;45(2):458-63. doi: 10.1128/iai.45.2.458-463.1984.
10
Differential complement activation and susceptibility to human serum bactericidal action by Vibrio species.弧菌属细菌的补体激活差异及对人血清杀菌作用的敏感性
Infect Immun. 1983 Dec;42(3):1187-90. doi: 10.1128/iai.42.3.1187-1190.1983.