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弧菌属细菌的补体激活差异及对人血清杀菌作用的敏感性

Differential complement activation and susceptibility to human serum bactericidal action by Vibrio species.

作者信息

Tamplin M L, Specter S, Rodrick G E, Friedman H

出版信息

Infect Immun. 1983 Dec;42(3):1187-90. doi: 10.1128/iai.42.3.1187-1190.1983.

Abstract

The ability of Vibrio vulnificus to resist human serum bactericidal action and to activate human complement was compared with similar cultures of Vibrio cholerae and Vibrio parahaemolyticus. Both V. vulnificus and V. parahaemolyticus had similar survival rates in sera and were much more resistant to killing than was V. cholerae. In contrast, V. vulnificus activated significantly less serum complement than did V. cholerae and V. parahaemolyticus. The relative ability of V. vulnificus to survive in serum and activate less complement than other Vibrio spp. tested may be related to its ability to cause chronic tissue infections and septicemias.

摘要

将创伤弧菌抵抗人血清杀菌作用及激活人补体的能力与霍乱弧菌和副溶血性弧菌的类似培养物进行了比较。创伤弧菌和副溶血性弧菌在血清中的存活率相似,且比霍乱弧菌更耐杀伤。相比之下,创伤弧菌激活的血清补体明显少于霍乱弧菌和副溶血性弧菌。创伤弧菌在血清中存活且激活的补体少于其他受试弧菌属的相对能力,可能与其引起慢性组织感染和败血症的能力有关。

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Disease caused by a marine vibrio--Vibrio vulnificus.由海洋弧菌——创伤弧菌引起的疾病。
N Engl J Med. 1982 Dec 23;307(26):1642. doi: 10.1056/NEJM198212233072609.
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Diseases of humans (other than cholera) caused by vibrios.由弧菌引起的人类疾病(霍乱除外)。
Annu Rev Microbiol. 1980;34:341-67. doi: 10.1146/annurev.mi.34.100180.002013.
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Serum-induced lysis of Pseudomonas aeruginosa.血清诱导的铜绿假单胞菌裂解
Eur J Clin Microbiol. 1982 Feb;1(1):1-6. doi: 10.1007/BF02014132.

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