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心血管疾病的基因和细胞疗法。

Gene- and cell-based therapy in cardiovascular diseases.

作者信息

Zhang Cuijuan, Du Zhihang, Chen Rui, Liu Xiaojing, Li Dan

机构信息

Department of Critical Care Medicine, The Affiliated Hospital of Qingdao University, Qingdao, 266000, Shandong, China.

Department of Cardiology, The Affiliated Hospital of Qingdao University, Qingdao, 266000, Shandong, China.

出版信息

J Cardiovasc Pharmacol. 2025 Apr 30;86(2):157-65. doi: 10.1097/FJC.0000000000001707.

Abstract

Cardiovascular disease (CVD) is one of the leading causes of mortality in humans, with a high prevalence. Moreover, this disease poses a serious threat to the economy. At present, treatment strategies are inadequate in both the prevention and cure of CVD. Thus, further investigations are required for the development of novel therapeutic options. Notably, gene- and cell-based therapies exhibit potential in the treatment of CVD. In the present article, gene- and cell-based therapies were reviewed in the context of CVD. The present review may provide a novel theoretical basis for improving the efficacy of CVD treatment, and demonstrate the potential of gene- and cell-based therapy in clinical practice. In addition, market analysis was carried out in the present study.

摘要

心血管疾病(CVD)是人类主要死因之一,患病率很高。此外,这种疾病对经济构成严重威胁。目前,心血管疾病的预防和治疗策略都不够完善。因此,需要进一步研究以开发新的治疗方案。值得注意的是,基于基因和细胞的疗法在心血管疾病治疗中显示出潜力。在本文中,对基于基因和细胞的疗法在心血管疾病背景下进行了综述。本综述可为提高心血管疾病治疗效果提供新的理论依据,并证明基于基因和细胞的疗法在临床实践中的潜力。此外,本研究还进行了市场分析。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/baf3/12333526/88b935eb46b0/jcvp-86-157-g001.jpg

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