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通过马尔可夫SEIR模型分析麻疹传播情况。

Analyzing measles spread through a Markovian SEIR model.

作者信息

Alnafisah Yousef, Sohaly M A

机构信息

Department of Mathematics, College of Science, Qassim University, P.O. Box 6644, 51452, Buraydah, Saudi Arabia.

Mathematics Department, Faculty of Science, Mansoura University, Mansoura, 35516, Egypt.

出版信息

Sci Rep. 2025 Apr 30;15(1):15183. doi: 10.1038/s41598-025-97318-3.

Abstract

In this study, we studied the spread of measles using the SEIR (Susceptible-Exposed-Infectious-Recovered) epidemic model, which we treated as a Markov chain. In epidemiology, a stationary distribution means that the disease will continue spreading until a vaccine is found. Our study presents a Markovian SEIR model to analyze the long-term behavior of measles transmission. Unlike deterministic models, our approach incorporates stochastic dynamics by computing the stationary distribution, offering insights into disease persistence. We employ the state reduction method to simplify complex computations and develop a Mathematica-based algorithm to efficiently determine steady-state probabilities. The findings provide a probabilistic understanding of measles spread, helping to assess vaccination strategies and long-term control measures.

摘要

在本研究中,我们使用SEIR(易感-暴露-感染-康复)流行模型研究了麻疹的传播,我们将其视为一个马尔可夫链。在流行病学中,平稳分布意味着疾病将持续传播,直到找到疫苗。我们的研究提出了一个马尔可夫SEIR模型,以分析麻疹传播的长期行为。与确定性模型不同,我们的方法通过计算平稳分布纳入了随机动力学,为疾病的持续存在提供了见解。我们采用状态约简方法简化复杂计算,并开发了一种基于Mathematica的算法来有效确定稳态概率。研究结果提供了对麻疹传播的概率性理解,有助于评估疫苗接种策略和长期控制措施。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/7a18/12043859/789197257aa6/41598_2025_97318_Fig1_HTML.jpg

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