Yang Yuangang, Li Bin, Luo Wei, Xu Bo, Luo Peng, Zhang Tongzuo, You Zhangqiang
Ecological Security and Protection Key Laboratory of Sichuan Province, Mianyang Normal University, Mianyang, Sichuan Province, China.
Key Laboratory of Adaptation and Evolution of Plateau Biota, Northwest Institute of Plateau Biology, Chinese Academy of Sciences, Xining, 810008, Qinghai, China.
Sci Data. 2025 May 1;12(1):727. doi: 10.1038/s41597-025-04796-1.
White-lipped deer (Przewalskium albirostris) is the sole species in the genus Przewalskium of the Cervidae family. And it is exclusively found in the Qinghai-Tibet Plateau, where it has evolved as a specialized deer on account of the extreme climates and geographical conditions. However, limited research on the genome of this species exists. Here, PacBio and Hi-C sequencing data were constructed to a high-quality Chromosome-level reference genome for the white-lipped deer. The assembly, totaling 2.99 GB, is composed of 34 chromosomes (32 autosomes and X, Y chromosomes), with a scaffold N50 length of 76.18 Mb. Furthermore, it achieved scores of 98.4% and 63.8 in Universal Single-Copy Ortholog (BUSCO) and quality value (QV), respectively. Subsequently, employing the egapx software for genome structural annotation, we identified a total of 21909 protein coding genes, annotating 21859 of them. The high-quality and completeness of our genome sequence and annotation was affirmed by these results. The assembly will significantly contribute to enhance the understanding of the adaptation mechanisms of the white-lipped deer to the extreme environments.
白唇鹿（Przewalskium albirostris）是鹿科Przewalskium属的唯一物种。它仅分布于青藏高原，由于极端的气候和地理条件，它已进化成为一种特殊的鹿类。然而，目前对该物种基因组的研究有限。在此，利用PacBio和Hi-C测序数据构建了高质量的白唇鹿染色体水平参考基因组。该基因组组装大小总计2.99GB，由34条染色体（32条常染色体和X、Y染色体）组成，支架N50长度为76.18Mb。此外，其通用单拷贝直系同源基因（BUSCO）得分和质量值（QV）分别达到98.4%和63.8。随后，使用egapx软件进行基因组结构注释，共鉴定出21909个蛋白质编码基因，其中21859个得到注释。这些结果证实了我们基因组序列和注释的高质量和完整性。该基因组组装将极大地有助于增进对白唇鹿适应极端环境机制的理解。
