Adeniyi Mayowa, Awosika Ayoola, Adamu Ayobami A
Department of Physiology (Environmental Physiology), Federal University of Health Sciences, Otupko, NGA.
College of Medicine, University of Illinois, Chicago, USA.
Cureus. 2025 Apr 1;17(4):e81569. doi: 10.7759/cureus.81569. eCollection 2025 Apr.
Background Understanding the relationship between orthostatic cardiovascular responses and anthropometric indices can provide insight into cardiovascular regulation, autonomic function, and disease risk stratification. Orthostatic responses like changes in systolic blood pressure, diastolic blood pressure, and pulse rate can be potentially influenced by body composition, height, weight, and body mass index (BMI). These anthropometric factors play a crucial role in maintaining hemodynamic stability during postural changes due to their complex interaction in modifying factors like systemic vascular resistance, cardiac output, and autonomic control. Alteration in this systemic interaction can be reflected by a change in the shock index (SI) and double product (DP), serving as surrogate markers for cardiovascular efficiency and myocardial workload, respectively. This study aims to investigate how the orthostatic response and the anthropometric indices relationship can be used to assess an individual's vulnerability to dysautonomia, hypotension, or cardiovascular stress during orthostasis. Materials and methods Thirty healthy female individuals, averaging 19.5 years, who satisfied the inclusion criteria were selected for the study. Body weight, height, and body mass index were measured. Blood pressure, pulse rate, and other parameters were determined at baseline (sitting position) and after 10 minutes of standing using standard procedures. Statistical significance was accepted at P<0.05. Results Although there was no correlation between the body mass index and cardiovascular parameters after 10 minutes of standing, body weight showed a strong positive correlation with the orthostatic shock index (r=0.803). On the other hand, height correlated negatively with orthostatic systolic blood pressure (r=-0.719) and orthostatic pulse pressure (r=-0.702), respectively. Conclusion The study's findings suggest that body weight and height can be used to predict orthostatic shock index, systolic blood pressure, and pulse pressure in young adult females. Assessing these orthostatic responses can help refine cardiovascular risk assessments, contributing to personalized medical interventions and improved long-term health outcomes.
背景 了解直立位心血管反应与人体测量指标之间的关系有助于深入了解心血管调节、自主神经功能和疾病风险分层。诸如收缩压、舒张压和脉搏率变化等直立位反应可能会受到身体成分、身高、体重和体重指数（BMI）的潜在影响。这些人体测量因素在姿势改变期间维持血液动力学稳定性方面起着关键作用，因为它们在改变全身血管阻力、心输出量和自主神经控制等因素方面存在复杂的相互作用。这种全身相互作用的改变可以通过休克指数（SI）和双乘积（DP）的变化反映出来，它们分别作为心血管效率和心肌工作负荷的替代指标。本研究旨在探讨直立位反应与人体测量指标之间的关系如何用于评估个体在直立位时发生自主神经功能障碍、低血压或心血管应激的易感性。
材料与方法 选择30名平均年龄为19.5岁且符合纳入标准的健康女性个体进行研究。测量体重、身高和体重指数。使用标准程序在基线（坐位）和站立10分钟后测定血压、脉搏率和其他参数。P<0.05时接受统计学显著性。
结果 虽然站立10分钟后体重指数与心血管参数之间无相关性，但体重与直立位休克指数呈强正相关（r=0.803）。另一方面，身高分别与直立位收缩压（r=-0.719）和直立位脉压（r=-0.702）呈负相关。
结论 该研究结果表明，体重和身高可用于预测年轻成年女性的直立位休克指数、收缩压和脉压。评估这些直立位反应有助于完善心血管风险评估，有助于个性化医疗干预并改善长期健康结局。
