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[肿瘤康复前准备与运动]

[Prehabilitation and sport in oncology].

作者信息

Wiskemann Joachim, Köppel Maximilian

机构信息

AG Onkologische Sport- und Bewegungstherapie, Abteilung Medizinische Onkologie, Nationales Centrum für Tumorerkrankungen (NCT) Heidelberg, Universitätsklinikum Heidelberg, Im Neuenheimer Feld 460, Heidelberg, Deutschland.

出版信息

Chirurgie (Heidelb). 2025 Jun;96(6):454-458. doi: 10.1007/s00104-025-02294-z. Epub 2025 May 2.

DOI:10.1007/s00104-025-02294-z
PMID:40314820
Abstract

Numerous randomized controlled trials confirm the clinical importance of exercise therapy in the management of side effects of cancer treatment. Physically active cancer patients also have a better prognosis. Since it has been known that the physical performance level before surgery is a strong prognostic factor for the occurrence of perioperative complications, the focus of interest has also been on exercise therapy-based prehabilitation. Studies in this field show that even very short interventions (2-4 weeks) can achieve lower perioperative complication rates, particularly for pulmonary complications. Even if the evidence is still limited, it can be concluded that every patient should be offered exercise therapy prehabilitation in preparation for major pulmonary or gastrointestinal surgical interventions. However, there are so far hardly any treatment structures that make this currently possible.

摘要

大量随机对照试验证实了运动疗法在癌症治疗副作用管理中的临床重要性。积极进行身体活动的癌症患者预后也更好。由于术前身体机能水平是围手术期并发症发生的一个强有力的预后因素,因此人们的关注焦点也集中在了基于运动疗法的术前康复上。该领域的研究表明,即使是非常短的干预措施(2 - 4周)也能降低围手术期并发症发生率,尤其是肺部并发症。即使证据仍然有限,但可以得出结论,对于准备进行重大肺部或胃肠道手术的患者,都应提供运动疗法术前康复。然而,目前几乎没有任何治疗结构能够实现这一点。

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1
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本文引用的文献

1
Grading the evidence for physical activity and any outcome in cancer survivors: An Umbrella review of 740 meta-analytic associations.对癌症幸存者体育活动及任何结局的证据进行分级:对740项荟萃分析关联的综合评价
Crit Rev Oncol Hematol. 2025 Mar;207:104602. doi: 10.1016/j.critrevonc.2024.104602. Epub 2024 Dec 25.
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Prehabilitative high-intensity interval training and resistance exercise in patients prior allogeneic stem cell transplantation.异体干细胞移植前的预康复高强度间歇训练和抗阻运动。
Sci Rep. 2023 Dec 12;13(1):22069. doi: 10.1038/s41598-023-49420-7.
3
Exploring the organisational structure of networks for exercise oncology provision: a social network analysis of OnkoAktiv.
探索运动肿瘤学服务网络的组织结构:OnkoAktiv 的社会网络分析。
BMC Health Serv Res. 2023 May 27;23(1):555. doi: 10.1186/s12913-023-09572-8.
4
Effect of Multimodal Prehabilitation on Reducing Postoperative Complications and Enhancing Functional Capacity Following Colorectal Cancer Surgery: The PREHAB Randomized Clinical Trial.多模式术前康复对减少结直肠癌手术后并发症和增强功能能力的影响:PREHAB 随机临床试验。
JAMA Surg. 2023 Jun 1;158(6):572-581. doi: 10.1001/jamasurg.2023.0198.
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Evidence base for exercise prehabilitation suggests favourable outcomes for patients undergoing surgery for non-small cell lung cancer despite being of low therapeutic quality: a systematic review and meta-analysis.运动预康复的循证医学依据表明,对于接受非小细胞肺癌手术的患者,尽管治疗质量较低,但仍有良好的预后:一项系统评价和荟萃分析。
Eur J Surg Oncol. 2023 May;49(5):879-894. doi: 10.1016/j.ejso.2023.01.024. Epub 2023 Feb 4.
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Effects and duration of exercise-based prehabilitation in surgical therapy of colon and rectal cancer: a systematic review and meta-analysis.基于运动的术前康复在结直肠癌手术治疗中的效果和持续时间:系统评价和荟萃分析。
J Cancer Res Clin Oncol. 2022 Sep;148(9):2187-2213. doi: 10.1007/s00432-022-04088-w. Epub 2022 Jun 13.
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Cancer Med. 2021 Jul;10(13):4195-4205. doi: 10.1002/cam4.4021. Epub 2021 Jun 10.
8
Preoperative Cardiopulmonary Exercise Test Associated with Postoperative Outcomes in Patients Undergoing Cancer Surgery: A Systematic Review and Meta-Analyses.术前心肺运动试验与癌症手术患者术后结局的关系:系统评价和荟萃分析。
Ann Surg Oncol. 2021 Nov;28(12):7120-7146. doi: 10.1245/s10434-021-10251-3. Epub 2021 Jun 8.
9
Preoperative exercise interventions to optimize continence outcomes following radical prostatectomy.术前运动干预以优化根治性前列腺切除术后的控尿效果。
Nat Rev Urol. 2021 May;18(5):259-281. doi: 10.1038/s41585-021-00445-5. Epub 2021 Apr 8.
10
Prehabilitation in head and neck cancer patients: a literature review.头颈部癌症患者的预康复:文献综述。
J Otolaryngol Head Neck Surg. 2021 Jan 6;50(1):2. doi: 10.1186/s40463-020-00486-7.