van Rens Matheus F P T, Hugill Kevin, van der Lee Robin, Piersigilli Fiammetta, Francia Airene L V, van Loon Fredericus H J, Bayoumi Mohammad A A
Neonatal Intensive Care Unit, Radboud University Medical Center, Amalia Children's Hospital, Nijmegen, The Netherlands.
Department of Nursing and Midwifery Education, Hamad Medical Corporation, Doha, Qatar.
Sci Rep. 2025 May 2;15(1):15373. doi: 10.1038/s41598-025-00301-1.
Neonatal-short peripheral intravenous catheters (n-SPCs) and neonatal-long peripheral intravenous catheters (n-LPCs) are widely used for short-term vascular access in neonates. A retrospective single-centred cohort study was conducted in the neonatal intensive care unit between 2019 and 2022 to compare the 2 types of catheters. A total of 34,464 catheter insertions were analysed (32,885 n-SPCs, 1,579 n-LPCs). n-LPCs had longer dwell time (48:27 ± 39:08 h versus 34:01 ± 33:31 h, p < 0.001). Accidental removals were lower in n-LPCs (0.3% versus 2.6%, p < 0.001). n-LPCs had higher rates of phlebitis (16.1% versus 6.6%, p < 0.001) and peripheral intravenous infiltration or extravasation (PIVIE) rate (40.0% versus 29.9%). Severe PIVIE (≥ 30% severity) was higher in n-LPCs (8.5% versus 2.8%, p < 0.001). n-LPCs offer a more stable and effective option for peripheral vascular access in neonates. Their use should be balanced with strategies to reduce the risk of phlebitis and severe PIVIE.
新生儿短外周静脉导管（n-SPCs）和新生儿长外周静脉导管（n-LPCs）广泛用于新生儿的短期血管通路。2019年至2022年期间，在新生儿重症监护病房进行了一项回顾性单中心队列研究，以比较这两种类型的导管。共分析了34464次导管插入情况（32885次n-SPCs，1579次n-LPCs）。n-LPCs的留置时间更长（48:27±39:08小时 vs 34:01±33:31小时，p<0.001）。n-LPCs的意外拔除率较低（0.3% vs 2.6%，p<0.001）。n-LPCs的静脉炎发生率较高（16.1% vs 6.6%，p<0.001），外周静脉浸润或外渗（PIVIE）率也较高（40.0% vs 29.9%）。n-LPCs中严重PIVIE（严重程度≥30%）的发生率更高（8.5% vs 2.8%，p<0.001）。n-LPCs为新生儿外周血管通路提供了一种更稳定、有效的选择。其使用应与降低静脉炎和严重PIVIE风险的策略相平衡。
