Mahalleh Mehrdad, Narimani-Javid Roozbeh, Izadpanahi Kasra, Eshraghi Reza, Behboodi Kiyarash, Afzalian Arian, Hashempoor Anahita, Thachil Rosy, May Heidi, Waheed Abdul, Aronow Wilbert S, Soleimani Hamidreza, Hosseini Kaveh
Rheumatology Research Center, Tehran University of Medical Sciences, Tehran, Iran.
Tehran Heart Center, Cardiovascular Diseases Research Institute, Tehran University of Medical Sciences, Tehran, Iran.
BMC Cardiovasc Disord. 2025 May 2;25(1):346. doi: 10.1186/s12872-025-04770-0.
Worldwide, ischemic heart disease is less prevalent in women than in men, but this gap has narrowed in recent decades. This study aims to evaluate trends and gender differences in the global burden of ischemic heart disease (IHD) across demographics and regions from 1990 to 2021.
We utilized the data of the Global Burden of Disease Study from 1990 to 2021. The standard epidemiological measurements, including incidence, prevalence, mortality rates, years of life lost (YLLs), years lived with disability (YLDs), and disability-adjusted life years (DALYs), were obtained to estimate the burden of IHD concerning age, sex, and the sociodemographic index, allowing for comparisons over time.
The sex parity ratio (SPR), defined as the ratio of females to males, has increased globally. The SPR of age-standardized prevalence (ASPR) and age-standardized incidence (ASIR) rose from 0.610 to 0.631 in 1990 to 0.653 and 0.670 in 2021, respectively. From 1990 to 2021, the SPRs for ASPR and ASIR of IHD increased across all age groups. However, the SPRs for the age-standardized mortality rate (ASMR) and the age-standardized DALY rates (ASDR) of IHD declined. This decrease in the SPR for both ASMR and ASDR of IHD was observed in most regions of this study.
While progress has been made in reducing the burden of IHD, the increasing sex disparities in specific regions and age groups emphasize the need for continuous monitoring, adaptive health policies, and sex-specific healthcare practices to ensure equitable health outcomes for all populations.
not applicable.
在全球范围内，缺血性心脏病在女性中的患病率低于男性，但近几十年来这一差距已有所缩小。本研究旨在评估1990年至2021年期间全球缺血性心脏病（IHD）负担在不同人口统计学和地区的趋势及性别差异。
我们利用了1990年至2021年全球疾病负担研究的数据。获取了包括发病率、患病率、死亡率、寿命损失年数（YLLs）、带病生存年数（YLDs）和伤残调整生命年（DALYs）等标准流行病学指标，以估计IHD在年龄、性别和社会人口指数方面的负担，从而能够进行随时间的比较。
全球范围内，女性与男性的比例（SPR）有所上升。年龄标准化患病率（ASPR）和年龄标准化发病率（ASIR）的SPR分别从1990年的0.610和0.631上升至2021年的0.653和0.670。1990年至2021年期间，IHD的ASPR和ASIR的SPR在所有年龄组中均有所增加。然而，IHD的年龄标准化死亡率（ASMR）和年龄标准化DALY率（ASDR）的SPR有所下降。本研究的大多数地区都观察到IHD的ASMR和ASDR的SPR出现了这种下降。
虽然在减轻IHD负担方面取得了进展，但特定地区和年龄组中不断增加的性别差异凸显了持续监测、适应性健康政策以及针对性别的医疗实践的必要性，以确保所有人群都能获得公平的健康结果。
不适用。
