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脑脊液溶菌酶水平测定在神经系统疾病诊断中的价值。

The value of the measurement of cerebrospinal fluid levels of lysozyme in the diagnosis of neurological disease.

作者信息

Firth G, Rees J, McKeran R O

出版信息

J Neurol Neurosurg Psychiatry. 1985 Jul;48(7):709-12. doi: 10.1136/jnnp.48.7.709.

Abstract

A turbidimetric technique has been adapted to yield maximum sensitivity for the measurement of lysozyme in cerebrospinal fluid. One hundred and ninety-eight patients were studied over a total period of 9 months using this technique. In addition to the considerably elevated levels known to occur in cases of bacterial and fungal meningitis, increased activity was also demonstrated in cases of subarachnoid haemorrhage and in certain inflammatory conditions. Normal or marginally increased levels were seen in cases of viral meningitis and encephalitis.

摘要

一种比浊法技术已被采用,以实现对脑脊液中溶菌酶测量的最大灵敏度。在9个月的总时间内,使用该技术对198名患者进行了研究。除了已知在细菌性和真菌性脑膜炎病例中出现的显著升高水平外,蛛网膜下腔出血病例和某些炎症性疾病中也显示出活性增加。在病毒性脑膜炎和脑炎病例中观察到正常或略有升高的水平。

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引用本文的文献

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Lysozymes in the animal kingdom.动物王国中的溶菌酶。
J Biosci. 2010 Mar;35(1):127-60. doi: 10.1007/s12038-010-0015-5.

本文引用的文献

3
Photometric determination of lysozyme activity.溶菌酶活性的光度测定。
Proc Soc Exp Biol Med. 1955 Jul;89(3):401-3. doi: 10.3181/00379727-89-21824.
4
Hazards of lumbar puncture.腰椎穿刺的风险
Br Med J (Clin Res Ed). 1982 Nov 27;285(6354):1521-2. doi: 10.1136/bmj.285.6354.1521.
9
Editorial: Lysozyme.社论:溶菌酶
N Engl J Med. 1975 Feb 20;292(8):424-5. doi: 10.1056/NEJM197502202920813.

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