McSwiney Niamh Theresa, Hutchison Eliza, Wainman Hannah
University Hospitals Dorset NHS Foundation Trust, Bournemouth, UK.
North Bristol NHS Trust, Bristol, UK; University Hospitals Bristol and Weston NHS Foundation Trust, Bristol, UK.
Clin Med (Lond). 2025 May;25(3):100316. doi: 10.1016/j.clinme.2025.100316. Epub 2025 May 2.
Pregnancy is associated with a wide range of cutaneous changes. Some are physiological and triggered by normal hormonal fluctuations during pregnancy. There are also a small number of pathological pruritic eruptions that exclusively occur during pregnancy, known as pregnancy-specific dermatoses (PSDs). In patients presenting with a PSD, features often include severe pruritus and characteristic inflammatory skin changes differing in onset, morphology and configuration. This article gives an overview of benign dermatological changes during pregnancy and the most important presentations of PSDs in order of prevalence: atopic eruption of pregnancy, polymorphic eruption of pregnancy, pemphigoid gestationis and pustular psoriasis of pregnancy. Importantly, we outline how a resident physician can identify these disorders, how to initiate management and when a specialty referral for further investigations and monitoring of the mother and unborn fetus is warranted.
怀孕与多种皮肤变化相关。有些是生理性的，由孕期正常的激素波动引发。也有少数仅在孕期出现的病理性瘙痒性皮疹，称为妊娠特异性皮肤病（PSD）。患有PSD的患者，其特征通常包括严重瘙痒以及在发病、形态和形态方面不同的特征性炎症性皮肤变化。本文概述了孕期的良性皮肤变化以及PSD的最重要表现形式，并按患病率排序：妊娠特应性皮疹、妊娠多形性皮疹、妊娠类天疱疮和妊娠脓疱型银屑病。重要的是，我们概述了住院医师如何识别这些疾病、如何开始管理以及何时需要专科转诊以对母亲和未出生胎儿进行进一步检查和监测。
