Liu Xiaofeng, Wang Qi, Zhang Yao, Feng Ziwei, Guan Rongfa
College of Food Science and Technology, Zhejiang University of Technology, Zhejiang, Hangzhou 310014, China.
Zhejiang Provincial Key Lab for Chem and Bio Processing Technology of Farm Produces, School of Biological and Chemical Engineering, Zhejiang University of Science and Technology, Zhejiang, Hangzhou 310023, China.
ACS Omega. 2025 Apr 18;10(16):15908-15922. doi: 10.1021/acsomega.5c01669. eCollection 2025 Apr 29.
As a fungus endemic to Taiwan, contains a variety of medicinally active substances, such as polysaccharides, triterpenoids, maleic acid and succinic acid derivatives, and ubiquinone derivatives. has attracted widespread attention due to its uniqueness, rarity, remarkable efficacy, and high economic value. In this work, we analyze the recent progress and future development of the artificial culture of mycelium of . This Review focuses on the types, properties, functions, and mechanisms of action of the characteristic active substances of and summarizes the methods of metabolic regulation and biosynthesis of the characteristic active substances. This Review provides valuable information for research on the metabolic regulation and efficacy analysis of the active substances and provides a theoretical basis for the in-depth development of the active ingredients in .
作为台湾特有的一种真菌，含有多种药用活性物质，如多糖、三萜类化合物、马来酸和琥珀酸衍生物以及辅酶Q衍生物。由于其独特性、稀有性、显著疗效和高经济价值，已引起广泛关注。在这项工作中，我们分析了该真菌菌丝体人工培养的最新进展和未来发展。本综述重点关注该真菌特征活性物质的类型、性质、功能和作用机制，并总结了特征活性物质的代谢调控和生物合成方法。本综述为活性物质的代谢调控和功效分析研究提供了有价值的信息，并为该真菌活性成分的深入开发提供了理论依据。
