Anthropogenic climate change contributes to wildfire particulate matter and related mortality in the United States.

Climate change has increased forest fire extent in temperate and boreal North America. Here, we quantified the contribution of anthropogenic climate change to human mortality and economic burden from exposure to wildfire particulate matter at the county and state level across the contiguous US (2006 to 2020) by integrating climate projections, climate-wildfire models, wildfire smoke models, and emission and health impact modeling. Climate change contributed to approximately 15,000 wildfire particulate matter deaths over 15 years with interannual variability ranging from 130 (95% confidence interval: 64, 190) to 5100 (95% confidence interval: 2500, 7500) deaths and a cumulative economic burden of $160 billion. Approximately 34% of the additional deaths attributable to climate change occurred in 2020, costing $58 billion. The economic burden was highest in California, Oregon, and Washington. We suggest that absent abrupt changes in climate trajectories, land management, and population, the indirect impacts of climate change on human-health through wildfire smoke will escalate.