Kuntari Titik, Soleman Sani Rachman
Department of Public Health, Faculty of Medicine, Universitas Islam Indonesia, Yogyakarta, Indonesia.
Iran J Public Health. 2025 Apr;54(4):775-784. doi: 10.18502/ijph.v54i4.18415.
Medication non-adherence in hypertensive patients induced disease progressivity. Several factors contribute to non-adherence to treatment, such as multidrug prescription, the relationship between doctors and patients, and barriers in health services. We aimed to analyze determinants of medication non-adherence in productive-aged hypertensive patients in Indonesia.
A cross-sectional study was conducted among 58,148 respondents across Indonesia. Covariates are gender, age, education, occupation, residence, smoking status, family member, and history of stroke, cardiovascular and diabetes mellitus. Chi-square and Binary Logistic were performed using SPSS version 21.
More than half of the 58,148 hypertension patients in Indonesia (53.9%) are not taking their medication regularly. Chi-square analysis found that male gender, age groups (25 to 34, 35 to 44, 45 to 55, 56 to 64), graduated senior high school, employed workers, living in urban, smokers, four family members, and disease history correlated with non-adherence to treatment. However, Binary Logistic is obtained that age groups age groups (25 to 34, 35 to 44, 45 to 55 and 56 to 64; AOR=1.251, 1.609, 2.179, 2.424, respectively), employed workers (AOR=0.912), urban lived (AOR=1.085), smokers (AOR=0.853), more than four family members (AOR=1.146), stroke history (AOR=1.793), cardiovascular history (AOR=1.623), and diabetes mellitus history (AOR=1.489) found their significance level at 0.00. Two variables, gender and education, are not of significant.
Medication non-adherence in hypertensive patients has multifactorial aspects, such as in this study, including age, employed workers, living in urban areas, smokers, more prominent family members, and the history of the disease.
高血压患者的用药不依从会导致疾病进展。有几个因素导致治疗不依从，如多种药物处方、医患关系以及卫生服务中的障碍。我们旨在分析印度尼西亚生产年龄组高血压患者用药不依从的决定因素。
在印度尼西亚全国58148名受访者中进行了一项横断面研究。协变量包括性别、年龄、教育程度、职业、居住地、吸烟状况、家庭成员以及中风、心血管疾病和糖尿病病史。使用SPSS 21版进行卡方检验和二元逻辑回归分析。
印度尼西亚58148名高血压患者中，超过一半（53.9%）未规律服药。卡方分析发现，男性、年龄组（25至34岁、35至44岁、45至55岁、56至64岁）、高中毕业生、在职人员、居住在城市、吸烟者、四名家庭成员以及疾病史与治疗不依从相关。然而，二元逻辑回归分析得出，年龄组（25至34岁、35至44岁、45至55岁和56至64岁；调整后比值比分别为1.251、1.609、2.179、2.424）、在职人员（调整后比值比=0.912）、居住在城市（调整后比值比=1.085）、吸烟者（调整后比值比=0.853）、四名以上家庭成员（调整后比值比=1.146）、中风病史（调整后比值比=1.793）、心血管疾病史（调整后比值比=1.623）和糖尿病病史（调整后比值比=1.489）在0.00水平具有统计学意义。两个变量，即性别和教育程度，无统计学意义。
高血压患者的用药不依从具有多因素特点，如本研究中包括年龄、在职人员、居住在城市地区、吸烟者、家庭成员较多以及疾病史等。
