Xu Yan, Yin Yan, Yang Zai-Quan, Li Jing, Guo Li-Na, Ma Chao
Department of Medical Cosmetology, Cangzhou Central Hospital, Cangzhou, Hebei, 061001, People's Republic of China.
Department of Infectious Diseases, Cangzhou Infectious Disease Hospital, Cangzhou, Hebei, 061001, People's Republic of China.
Ther Clin Risk Manag. 2025 Apr 28;21:575-582. doi: 10.2147/TCRM.S508522. eCollection 2025.
To observe the clinical efficacy of microplasma radiofrequency in treating post-traumatic pigmentary deposition using VISIA quantitative analysis, an innovative approach not previously emphasized in microplasma radiofrequency studies.
Twenty patients with post-traumatic pigmentary deposition, treated at Cangzhou Central Hospital between July 2022 and December 2022, were selected. Pigmented areas were divided into four regions (A: control; B, C, D: treated with increasing energy parameters). Adverse effects (erythema, edema, micro-crusts, pruritus) were monitored at 2, 4, and 6 weeks post-treatment using CTCAE v5.0 criteria. Pigmentary deposition scores and VISIA parameters (spots, ultraviolet spots, red areas, brown spots) were evaluated.
At 2, 4, and 6 weeks, Groups B, C, D showed significant reductions in pigment scores and VISIA parameters vs Group A (P < 0.05), with Group D (highest energy) achieving maximal improvement. Transient mild-moderate erythema (60-100%), edema (40-80%), and micro-crusts (20-60%) occurred in treated groups, resolving spontaneously within 14 days; no severe adverse events were observed.
Microplasma radiofrequency significantly improves post-traumatic pigmentary deposition, with energy-dependent efficacy. Despite transient side effects at higher energies, its favorable safety profile supports clinical adoption. VISIA quantitative analysis provides robust objective evaluation, advancing standardization in pigment management.
采用VISIA定量分析观察微等离子体射频治疗创伤后色素沉着的临床疗效,这是一种在微等离子体射频研究中此前未被重点强调的创新方法。
选取2022年7月至2022年12月在沧州市中心医院接受治疗的20例创伤后色素沉着患者。将色素沉着区域分为四个区域(A:对照;B、C、D:用递增能量参数治疗)。使用CTCAE v5.0标准在治疗后2周、4周和6周监测不良反应(红斑、水肿、微痂、瘙痒)。评估色素沉着评分和VISIA参数(斑点、紫外线斑点、红色区域、褐色斑点)。
在2周、4周和6周时,B组、C组、D组的色素评分和VISIA参数与A组相比显著降低(P<0.05),D组(能量最高)改善最大。治疗组出现短暂的轻至中度红斑(60 - 100%)、水肿(40 - 80%)和微痂(20 - 60%),在14天内自发消退;未观察到严重不良事件。
微等离子体射频显著改善创伤后色素沉着,疗效与能量有关。尽管高能量时会出现短暂副作用,但其良好的安全性支持临床应用。VISIA定量分析提供了有力的客观评估,推动了色素沉着管理的标准化。