Solash Bayley, Cheema Jagjit S, Freire Mila, Benito Javier, Pang Daniel S J
Faculty of Veterinary Medicine, University of Calgary, 3280 Hospital Drive NW, Calgary, Alberta T2N 4Z6 (Solash, Pang); City of Calgary Animal Services Centre Clinic, 2201 Portland Street SE, Calgary, Alberta T2G 4M7 (Cheema); Faculty of Veterinary Medicine, Université de Montréal, 3200 Rue Sicotte, Saint-Hyacinthe, Quebec J2S 2M2 (Freire, Benito, Pang).
Can Vet J. 2025 May;66(5):537-545.
To compare sedation following premedication delivered subcutaneous (SC) injection at or adjacent to the Governing Vessel 20 acupuncture location (GV20adj), interscapular SC injection (iscapSC), or lumbar epaxial intramuscular (IM) injection.
Cats receiving ovariohysterectomy or castration surgery, randomly allocated to GV20adj ( = 18), iscapSC ( = 18), or IM ( = 20) groups.
Premedication consisted of dexmedetomidine (10 μg/kg) and methadone (0.2 mg/kg). Sedation, infrared temperature (GV20adj and iscapSC sites), and signs of nausea and vomiting were recorded.
The GV20adj injection resulted in greater sedation than iscapSC injection ( < 0.05) and similar sedation compared to IM injection. Sedation was more consistent with GV20adj than IM injection. Site temperature was higher at the GV20adj site than the iscapSC site ( < 0.0001). Nausea symptoms were similar between groups ( = 0.209), with increased vomiting in the iscapSC group (15/18 cats) compared to GV20adj (8/18, = 0.035) and IM groups (9/20, = 0.021).
Sedation GV20adj injection was similar to, but more consistent than, IM injection, and superior to iscapSC injection. Higher GV20adj site temperature suggested greater perfusion, potentially explaining differences in sedation and vomiting.
The GV20adj injection route in cats is a viable route for premedication or sedation.
比较在督脉20穴位(GV20adj)处或其附近进行皮下(SC)注射、肩胛间皮下注射(iscapSC)或腰部轴旁肌内注射(IM)进行术前用药后的镇静效果。
接受卵巢子宫切除术或去势手术的猫,随机分为GV20adj组(n = 18)、iscapSC组(n = 18)或IM组(n = 20)。
术前用药包括右美托咪定(10μg/kg)和美沙酮(0.2mg/kg)。记录镇静效果、红外温度(GV20adj和iscapSC部位)以及恶心和呕吐症状。
GV20adj注射产生的镇静效果比iscapSC注射更强(P < 0.05),与IM注射产生的镇静效果相似。与IM注射相比,GV20adj注射的镇静效果更稳定。GV20adj部位的温度高于iscapSC部位(P < 0.0001)。各组之间恶心症状相似(P = 0.209),但iscapSC组呕吐增加(15/18只猫),与GV20adj组(8/18,P = 0.035)和IM组(9/20,P = 0.021)相比。
GV20adj注射的镇静效果与IM注射相似,但更稳定,且优于iscapSC注射。GV20adj部位较高的温度表明灌注更好,这可能解释了镇静和呕吐方面的差异。
猫的GV20adj注射途径是术前用药或镇静的可行途径。