Colovini Francielle, Horn Priscila Aparecida, Zeni Ana Lúcia Bertarello
Laboratório de Avaliação de Substâncias Bioativas, Departamento de Ciências Naturais, Universidade Regional de Blumenau, Blumenau, Santa Catarina, Brazil.
Programa de Pós-Graduação em Biodiversidade, Departamento de Ciências Naturais, Universidade Regional de Blumenau, Blumenau, Santa Catarina, Brazil.
Nat Prod Res. 2025 May 5:1-8. doi: 10.1080/14786419.2025.2498074.
Chronic exposure to the sun is associated with photoaging and skin cancer and plants are an alternative for green sunscreen formulations. Swartz (Sw.), a species endemic to Brazil, has been used in traditional medicine to treat inflammation and diarrhoea. This study aimed to investigate the seasonal composition and antioxidant and photoprotective activities of leaves aqueous extract (PGLE), and the impact of climate data on the compound production for 2 years. The higher amounts of phenolics were found in the autumn and spring, by LC-MS/MS methods, showing a correlation with precipitation for phenolics and flavonoids, humidity for carotenoids, minimum and maximum temperatures for quercetin, and cloudiness for gallic acid. All seasons demonstrated high antioxidant capacity associated with phenolics, quercetin, and catechin. The high phenolic composition, carotenoids, tannins, and flavonoids were correlated with the photoprotection. Therefore, the results suggested that PGLE has potential photoprotective and antioxidant agents suitable for therapeutic applications, such as green sunscreens.
长期暴露在阳光下会导致光老化和皮肤癌，而植物是绿色防晒配方的替代品。巴西特有的物种斯沃茨（Sw.）已被用于传统医学中治疗炎症和腹泻。本研究旨在调查叶片水提取物（PGLE）的季节性成分、抗氧化和光保护活性，以及气候数据对两年内化合物产量的影响。通过液相色谱-串联质谱法（LC-MS/MS）发现，秋季和春季的酚类物质含量较高，表明酚类和黄酮类物质与降水量、类胡萝卜素与湿度、槲皮素与最低和最高温度、没食子酸与云量之间存在相关性。所有季节都表现出与酚类、槲皮素和儿茶素相关的高抗氧化能力。高酚类成分、类胡萝卜素、单宁和黄酮类物质与光保护作用相关。因此，结果表明PGLE具有适合治疗应用的潜在光保护和抗氧化剂，如绿色防晒霜。
