Advances in photothermal therapy for cancer and bacterial cells ablation using various nanomaterials.

Bacterial pathogens can cause severe infections leading to mortality and morbidity. The current method of treatment for bacteria is the use of multiple antibiotics. Due to the overuse of antibiotics, many bacteria have become antibiotic-resistant. An alternative and effective treatment for bacterial infection is needed, and photothermal therapy (PTT) has emerged as a new solution for treating bacterial infection. Similarly, one of the main challenges in cancer treatment is the overuse of drugs that have multiple side effects. In recent years, there have been significantly more research activities in alternative therapy for pathogenic bacteria and cancer cells. Recently, PTT has also been used to treat various medical conditions like cancer, bacterial infections, or bacterial biofilm. Different kinds of nanomaterials like gold nanoparticles (AuNPs), Graphene Oxide (GO), Carbon nanotubes (CNTs), etc. have been explored for this purpose. In this particular review, we will elaborate on different kinds of nanomaterials (metallic, non-metallic, polymeric) widely used for PTT applications for bacteria and cancer cells. These kinds of nanoparticles have strong absorption in the NIR region and can convert light energy into heat energy, leading to hyperthermia. Further different types of PTT will be elaborated on, along with challenges and future applications. The current review will pave a new way for the therapeutic potential of different nanomaterials for bacterial infection and cancer treatment.