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一名青少年颅内毛霉菌病引发卒中警报:病例报告及儿科病例系统评价

Intracranial Mucormycosis in an Adolescent Triggering a Stroke Alert: A Case Report and a Systematic Review of Pediatric Cases.

作者信息

El Atrache Rima, Mizerik Melissa, Ruiz Lopez Joaquin Francisco, Engstrom Eric, Salazar Karla Patricia, Guzman-Karlsson Mikael C, Davila-Williams Daniel, Sen Sonali, Fisher Kristen S, Erklauer Jennifer C

机构信息

Department of Pediatrics, Division of Neurology and Developmental Neurosciences, Baylor College of Medicine, Texas Children's Hospital, Houston, TX, USA.

Department of Neuroradiology, Baylor College of Medicine, Houston, TX, USA.

出版信息

J Child Neurol. 2025 Sep;40(8):678-685. doi: 10.1177/08830738251334939. Epub 2025 May 7.

Abstract

Mucormycosis is a rare, life-threatening opportunistic infection primarily affecting immunocompromised patients. The available literature on infections of the central nervous system (CNS) in children is very limited. We present the case of an immunocompromised adolescent with intracranial mucormycosis due to manifesting with stroke-like symptoms. This case highlights this rare condition's diagnostic complexity and management challenges. We include a review of the available literature on pediatric CNS infections to increase awareness among health care providers.

摘要

毛霉菌病是一种罕见的、危及生命的机会性感染,主要影响免疫功能低下的患者。关于儿童中枢神经系统(CNS)感染的现有文献非常有限。我们报告一例免疫功能低下的青少年因出现类似中风的症状而患有颅内毛霉菌病的病例。该病例突出了这种罕见疾病的诊断复杂性和管理挑战。我们纳入了对儿科中枢神经系统感染现有文献的综述,以提高医疗服务提供者的认识。

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