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一名14岁男孩大网膜发生的腹膜良性囊性间皮瘤

Benign Cystic Mesothelioma of the Peritoneum Arising at the Greater Omentum in a 14-Year-Old Boy.

作者信息

Hirayama Yutaka, Higashidate Naruki, Nakaya Kengo, Iinuma Yasushi

机构信息

Department of Pediatric Surgery, Niigata City General Hospital, Niigata, Niigata, Japan.

出版信息

Surg Case Rep. 2025;11(1). doi: 10.70352/scrj.cr.24-0085. Epub 2025 May 1.

Abstract

INTRODUCTION

Mesothelioma arises from mesothelial cells. This tumor is very rare among pediatric abdominal neoplasms. We herein report an extremely rare case of acute abdomen with cystic mesothelioma of the peritoneum in a child.

CASE PRESENTATION

A 14-year-old boy was referred to our hospital for emergency surgery. Surgery revealed a primary tumor arising from the greater omentum. The tumor was macroscopically diagnosed as a benign omental lymphangioma and was resected en bloc with the greater omentum. A histopathological examination of the tumor revealed a simple columnar epithelium-like mesothelioma with poor cell-atypia. Immunohistochemical examination showed antibody reactivity in the cyst epithelium, including an anti-calretinin antibody. The final pathological diagnosis was a mesothelioma originating from the peritoneum.

CONCLUSIONS

In pediatric cases diagnosed with cystic lymphatic malformation, the possibility of peritoneal mesothelioma needs to be considered and carefully confirmed or ruled out.

摘要

引言

间皮瘤起源于间皮细胞。这种肿瘤在儿童腹部肿瘤中非常罕见。我们在此报告一例极为罕见的儿童急性腹痛伴腹膜囊性间皮瘤病例。

病例介绍

一名14岁男孩因急诊手术被转诊至我院。手术发现一个起源于大网膜的原发性肿瘤。该肿瘤在宏观上被诊断为良性网膜淋巴管瘤,并与大网膜一并整块切除。对肿瘤进行组织病理学检查显示为细胞异型性较差的单层柱状上皮样间皮瘤。免疫组织化学检查显示囊肿上皮中有抗体反应,包括抗钙结合蛋白抗体。最终病理诊断为起源于腹膜的间皮瘤。

结论

在诊断为囊性淋巴管畸形的儿科病例中,需要考虑并仔细确认或排除腹膜间皮瘤的可能性。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/be9d/12055440/1eef13ba11be/scr-11-01-24-0085-g001.jpg

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