Wang Fangying, Zhao Qingyu, Liang Guanmian, Wu Wanying
School of Nursing, Zhejiang Chinese Medical University, Hangzhou, China.
Hangzhou Linping Vocational High School, Hangzhou, China.
Asia Pac J Oncol Nurs. 2025 Mar 21;12:100690. doi: 10.1016/j.apjon.2025.100690. eCollection 2025 Dec.
This study aims to develop the Symptom Assessment Scale for Patients with Nasopharyngeal Cancer Undergoing Radiotherapy (SAS-NPC), based on the Symptom Experience Model.
In Phase 1, a content analysis of the literature and group discussions were conducted to construct an initial pool of 61 items. Following expert review by 16 specialists and cognitive interviews with 10 patients, the pool was refined to 56 items. In Phase 2, a convenience sampling method was used to recruit 625 patients with nasopharyngeal cancer (NPC) undergoing radiotherapy, who assessed and explored the scale items. Phase 3 focused on evaluating the scale's reliability and validity.
The SAS-NPC consists of 7 dimensions and 33 items. Reliability analysis revealed a Cronbach's α coefficient of 0.928 for the total scale, a split-half reliability of 0.790, and a retest reliability of 0.828. Validity analysis showed content validity indices for each item ranging from 0.833 to 1.000, with an overall content validity index of 0.970 for the scale. Exploratory factor analysis (EFA) identified 7 common factors, which accounted for 74.505% of the total variance. Confirmatory factor analysis (CFA) demonstrated good overall model fit.
The SAS-NPC comprehensively captures acute and long-term symptoms associated with patients with NPC undergoing radiotherapy. The scale exhibits strong reliability and validity, making it an ideal tool for assessing NPC symptom burden and facilitating clinical symptom management.
本研究旨在基于症状体验模型开发鼻咽癌放疗患者症状评估量表（SAS-NPC）。
在第一阶段，进行文献内容分析和小组讨论，构建了一个包含61个条目的初始池。经过16位专家的评审和对10名患者的认知访谈，该条目池被精简至56个条目。在第二阶段，采用便利抽样方法招募了625名接受放疗的鼻咽癌（NPC）患者，他们对量表条目进行了评估和探索。第三阶段重点评估量表的信效度。
SAS-NPC由7个维度和33个条目组成。信度分析显示，总量表的Cronbach's α系数为0.928，分半信度为0.790，重测信度为0.828。效度分析表明，各条目的内容效度指数在0.833至1.000之间，量表的总体内容效度指数为0.970。探索性因子分析（EFA）确定了7个共同因子，占总方差的74.505%。验证性因子分析（CFA）表明总体模型拟合良好。
SAS-NPC全面涵盖了鼻咽癌放疗患者的急性和长期症状。该量表具有较强的信效度，是评估鼻咽癌症状负担和促进临床症状管理的理想工具。
