Ferrari Ambra, Filippin Luca, Buiatti Marco, Parise Eugenio
CIMeC, Center for Mind/Brain Sciences, University of Trento, Rovereto, Italy.
Max Plank Institute for Psycholinguistics, Nijmegen, The Netherlands.
PLoS One. 2025 May 7;20(5):e0323179. doi: 10.1371/journal.pone.0323179. eCollection 2025.
Electroencephalography (EEG) is an established method for investigating neurocognitive functions during human development. In cognitive neuroscience, time-frequency analysis of the EEG is a widely used analytical approach. This paper introduces WTools, a new MATLAB-based toolbox for time-frequency analysis of EEG signals using complex wavelet transformation. WTools features an intuitive GUI that guides users through the analysis steps, focusing on essential parameters. Being free and open-source, it can be integrated and expanded with new features, making it a handy tool that is growing its popularity in developmental cognitive neuroscience. While the default settings follow established pipelines in developmental research, the toolbox also provides the flexibility to accommodate settings more commonly used in adult neuroscience. Here, we provide a detailed description of the WTools algorithm for wavelet transformation and we compare it with state-of-the-art methods implemented in EEGLAB. Alongside the official tool release, we offer a comprehensive, illustrated tutorial with sample infant EEG data designed to support novice users, enhance accessibility and promote the transparent and reproducible usage of WTools.
脑电图(EEG)是研究人类发育过程中神经认知功能的一种既定方法。在认知神经科学中,脑电图的时频分析是一种广泛使用的分析方法。本文介绍了WTools,这是一个基于MATLAB的新工具箱,用于使用复小波变换对脑电信号进行时频分析。WTools具有直观的图形用户界面(GUI),可指导用户完成分析步骤,重点关注关键参数。它免费且开源,可以集成新功能并进行扩展,使其成为一种方便的工具,在发育认知神经科学中越来越受欢迎。虽然默认设置遵循发育研究中的既定流程,但该工具箱也提供了灵活性,以适应成人神经科学中更常用的设置。在这里,我们详细描述了WTools的小波变换算法,并将其与EEGLAB中实现的最新方法进行了比较。除了正式发布工具外,我们还提供了一个全面的、有插图的教程,其中包含示例婴儿脑电数据,旨在支持新手用户,提高可及性,并促进WTools的透明和可重复使用。