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久坐行为与女性慢性盆腔疼痛之间的关联:一项系统评价与荟萃分析方案

Association between sedentary behaviour and chronic pelvic pain in women: a protocol for systematic review and meta-analysis.

作者信息

Tang Lei, Guo Yangyan, Wang Guohua

机构信息

Beijing University of Chinese Medicine, Beijing, China.

Beijing University of Chinese Medicine Third Affiliated Hospital, Beijing, Beijing, China

出版信息

BMJ Open. 2025 May 6;15(5):e091992. doi: 10.1136/bmjopen-2024-091992.

DOI:10.1136/bmjopen-2024-091992
PMID:40335148
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC12056639/
Abstract

INTRODUCTION

In light of the rising prevalence of sedentary behaviour worldwide, its impact on health has become a subject of growing interest. To clarify whether there is a significant correlation between sedentary behaviour and chronic pelvic pain in women and to explore its potential clinical implications, this study aims to provide a systematic review and meta-analysis of the association between the two. The findings of this study will inform the development of effective prevention and intervention strategies.

METHODS AND ANALYSIS

This study will conduct an exhaustive search across electronic databases, encompassing PubMed, Embase, Web of Science, the Cochrane Central Register of Controlled Trials and Scopus, for records published up until 26 June 2024. Two independent researchers will conduct the study selection, data extraction and assessment of bias risks, with any discrepancies resolved through the collaboration of a third reviewer. To accurately discern the underlying sources of heterogeneity, sensitivity, subgroup analyses and meta-regression will be conducted in parallel. Additionally, to ensure the rigour and integrity of our research, Begg's and Egger's tests will serve as the primary means of evaluating the potential for publication bias within the studies under consideration.

ETHICS AND DISSEMINATION

Ethical approval will not be required for this study, as it will use publicly accessible, non-identifiable data from the published literature. The research team will ensure data privacy and participant confidentiality through anonymised data processing and strict compliance with relevant regulations. The results of this study will be disseminated through publication in a peer-reviewed journal.

PROSPERO REGISTRATION NUMBER

CRD42024562443.

摘要

引言

鉴于全球久坐行为的患病率不断上升,其对健康的影响已成为一个日益受到关注的主题。为了阐明久坐行为与女性慢性盆腔疼痛之间是否存在显著相关性,并探讨其潜在的临床意义,本研究旨在对两者之间的关联进行系统综述和荟萃分析。本研究的结果将为制定有效的预防和干预策略提供依据。

方法与分析

本研究将对电子数据库进行全面检索,包括PubMed、Embase、Web of Science、Cochrane对照试验中央注册库和Scopus,检索截至2024年6月26日发表的记录。两名独立研究人员将进行研究筛选、数据提取和偏倚风险评估,如有分歧将通过第三名评审员的协作解决。为了准确识别异质性的潜在来源,将同时进行敏感性分析、亚组分析和元回归分析。此外,为确保我们研究的严谨性和完整性,Begg检验和Egger检验将作为评估所考虑研究中潜在发表偏倚的主要手段。

伦理与传播

本研究无需伦理批准,因为它将使用已发表文献中公开可用的、无法识别身份的数据。研究团队将通过匿名数据处理和严格遵守相关规定来确保数据隐私和参与者的保密性。本研究的结果将通过在同行评审期刊上发表进行传播。

PROSPERO注册号:CRD42024562443。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/f5d5/12056639/858c6e2ff515/bmjopen-15-5-g001.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/f5d5/12056639/858c6e2ff515/bmjopen-15-5-g001.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/f5d5/12056639/858c6e2ff515/bmjopen-15-5-g001.jpg

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本文引用的文献

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Nutr Metab (Lond). 2025 Feb 14;22(1):11. doi: 10.1186/s12986-025-00907-2.
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Occupational Sitting Time, Leisure Physical Activity, and All-Cause and Cardiovascular Disease Mortality.职业久坐时间、休闲体力活动与全因和心血管疾病死亡率。
JAMA Netw Open. 2024 Jan 2;7(1):e2350680. doi: 10.1001/jamanetworkopen.2023.50680.
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Understanding and addressing female pelvic pain - a multifaceted challenge.
理解并应对女性盆腔疼痛——一项多方面的挑战。
Acta Obstet Gynecol Scand. 2023 Oct;102(10):1248-1249. doi: 10.1111/aogs.14682.
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Sedentary behavior patterns and the risk of non-communicable diseases and all-cause mortality: A systematic review and meta-analysis.久坐行为模式与非传染性疾病和全因死亡率的风险:系统评价和荟萃分析。
Int J Nurs Stud. 2023 Oct;146:104563. doi: 10.1016/j.ijnurstu.2023.104563. Epub 2023 Jul 13.
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Pelvic venous congestion syndrome: female venous congestive syndromes and endovascular treatment options.盆腔静脉淤血综合征:女性静脉充血综合征及血管内治疗选择
CVIR Endovasc. 2023 Apr 20;6(1):25. doi: 10.1186/s42155-023-00365-y.
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Associations of daily sedentary behavior, physical activity, and sleep with irritable bowel syndrome: A prospective analysis of 362,193 participants.每日久坐行为、身体活动与睡眠与肠易激综合征的相关性:对 362193 名参与者的前瞻性分析。
J Sport Health Sci. 2024 Jan;13(1):72-80. doi: 10.1016/j.jshs.2023.02.002. Epub 2023 Feb 18.
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mHealth Intervention for Improving Pain, Quality of Life, and Functional Disability in Patients With Chronic Pain: Systematic Review.移动医疗干预对改善慢性疼痛患者疼痛、生活质量和功能障碍的系统评价。
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