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女性慢性盆腔疼痛管理中的当前挑战:从实验室到临床

Current Challenges in the Management of Chronic Pelvic Pain in Women: From Bench to Bedside.

作者信息

Siqueira-Campos Vânia Meira, de Deus Mariana Siqueira Campos, Poli-Neto Omero Benedicto, Rosa-E-Silva Julio Cesar, de Deus José Miguel, Conde Délio Marques

机构信息

Department of Obstetrics and Gynecology, School of Medicine, Federal University of Goiás, Goiânia, Goiás, Brazil.

Laboratory for Translational Data Science, Ribeirão Preto Medical School, University of São Paulo, Ribeirão Preto, São Paulo, Brazil.

出版信息

Int J Womens Health. 2022 Feb 18;14:225-244. doi: 10.2147/IJWH.S224891. eCollection 2022.

DOI:10.2147/IJWH.S224891
PMID:35210869
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC8863341/
Abstract

Chronic pelvic pain (CPP) affects a significant proportion of women worldwide And has a negative impact on several aspects of these women's lives including mental health, work, relationships and sexual function, among others. This set of factors ultimately reflects negatively on quality Of life. The physiopathology of CPP is complex and remains to be fully clarified; however, recent advances have increased understanding of the mechanisms involved in chronic pain in general, and more specifically, CPP. Nonetheless, even when a detailed clinical history is obtained, meticulous physical examination is performed and imaging resources are appropriately used, the organic cause of the pain may still fail to be identified in a substantial number of women with CPP. Management of CPP may therefore be challenging. This narrative review was aimed at adding to the available literature on the subject, presenting and discussing the principal characteristics of CPP in women. The paper highlights gaps in the literature while providing the most up-to-date evidence associated with the physiopathology and classification of pain, its diagnosis and treatment. In addition, current challenges in the management of women with CPP are discussed.

摘要

慢性盆腔疼痛(CPP)影响着全球相当一部分女性,对这些女性生活的多个方面产生负面影响,包括心理健康、工作、人际关系和性功能等。这一系列因素最终会对生活质量产生负面影响。CPP的病理生理学很复杂,仍有待充分阐明;然而,最近的进展使人们对一般慢性疼痛,尤其是CPP所涉及的机制有了更多了解。尽管如此,即使获取了详细的临床病史、进行了细致的体格检查并适当使用了影像学资源,在相当一部分CPP女性中,疼痛的器质性原因仍可能无法确定。因此,CPP的管理可能具有挑战性。这篇叙述性综述旨在补充该主题的现有文献,介绍和讨论女性CPP的主要特征。本文在强调文献空白的同时,提供了与疼痛的病理生理学、分类、诊断和治疗相关的最新证据。此外,还讨论了当前CPP女性管理中的挑战。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/e0a0/8863341/f73c7902050f/IJWH-14-225-g0003.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/e0a0/8863341/dfab05ff90d3/IJWH-14-225-g0001.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/e0a0/8863341/575b6b029375/IJWH-14-225-g0002.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/e0a0/8863341/f73c7902050f/IJWH-14-225-g0003.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/e0a0/8863341/dfab05ff90d3/IJWH-14-225-g0001.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/e0a0/8863341/575b6b029375/IJWH-14-225-g0002.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/e0a0/8863341/f73c7902050f/IJWH-14-225-g0003.jpg

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