Yang Yuting, Yuan Qiao, Zhou Qi, Yang Lili
Department of Nursing, The Fourth Affiliated Hospital of School of Medicine, and International School of Medicine, International Institutes of Medicine, Zhejiang University, Yiwu, Zhejiang, China.
Nursing Department, Hangzhou Normal University, Hangzhou, Zhejiang, China.
BMJ Open. 2024 Dec 26;14(12):e084460. doi: 10.1136/bmjopen-2024-084460.
Sedentary behaviour is associated with numerous adverse health outcomes in patients with cardiovascular disease, independent of physical activity. Related interventions have improved sedentary behaviour in patients with coronary heart disease (CHD). However, their effectiveness has remained inconclusive. This systematic review and meta-analysis aim to comprehensively examine the efficacy of interventions for patients with CHD, thereby contributing to future implementation decisions to improve sedentary behaviour.
This protocol follows the guidelines for the Preferred Reporting Items for Systematic Review and Meta-Analysis Protocols. Searches will be conducted in English and Chinese electronic databases from inception to 31 December 2024. All published randomised controlled trials and quasi-experimental studies that report on reducing sedentary behaviour in patients with CHD will be included. Two authors will independently conduct study selection, data extraction and quality assessment. Study quality will be assessed using validated tools appropriate for each study design. The overall meta-analyses for sedentary behaviour outcomes will be performed if the outcome data are sufficient and provide similar effect measures and subgroup analyses based on demographic characteristics, intervention duration, intervention types, intervention content and measurement tools. We will conduct a qualitative synthesis for studies that could not be quantitatively synthesised.
Ethical approval is not required for this review as no human participants will be involved. The results will be disseminated through a peer-reviewed journal publication or academic conference.
CRD42023466985.
久坐行为与心血管疾病患者的众多不良健康结局相关，且独立于身体活动。相关干预措施已改善了冠心病（CHD）患者的久坐行为。然而，其有效性仍不明确。本系统评价和荟萃分析旨在全面检验针对冠心病患者的干预措施的疗效，从而为未来改善久坐行为的实施决策提供参考。
本方案遵循系统评价和荟萃分析方案的首选报告项目指南。将在英文和中文电子数据库中进行检索，检索时间从建库至2024年12月31日。所有报告降低冠心病患者久坐行为的已发表随机对照试验和准实验研究都将被纳入。两名作者将独立进行研究筛选、数据提取和质量评估。将使用适用于每种研究设计的经过验证的工具评估研究质量。如果结局数据充足且提供相似的效应测量指标，将对久坐行为结局进行总体荟萃分析，并根据人口统计学特征、干预持续时间、干预类型、干预内容和测量工具进行亚组分析。对于无法进行定量合成的研究，我们将进行定性合成。
由于本评价不涉及人类参与者，因此无需伦理批准。研究结果将通过同行评审的期刊发表或学术会议进行传播。
PROSPERO注册号：CRD42023466985。
