To compare the safety and effectiveness of robot-assisted laparoscopic surgery and traditional laparoscopic surgery in the treatment of giant pheochromocytomas and paragangliomas (PPGL). A retrospective analysis was conducted using the data of patients who underwent surgery at our institution between January 2013 and November 2023 and whose postoperative pathological examination confirmed PPGL (n = 84). Patients were divided into the robot-assisted (n = 33) and laparoscopic (n = 51) groups. Baseline data and intraoperative and postoperative recovery conditions of the two groups were compared. There was no significant difference in the baseline data between the two groups. The time to resume food intake in the robot-assisted group was shorter than that in the laparoscopic group [2 (1-2) vs. 3 (2-3) days, p < 0.001], and the incidence of postoperative morbidity was also lower (15.2% vs. 43.1%, p = 0.009); however, operating room time was longer [265 (240-370) vs. 245 (205-297.5) min, p = 0.039], and overall hospitalization costs were higher [80336.38 (72,014.3-101,555.39) vs. 60,102.13 (43,059.205-88085.35) CNY, p = 0.003]. This study results indicate that robot-assisted laparoscopic surgery has a lower postoperative complication rate and faster postoperative gastrointestinal function recovery. However, the surgery is costlier and operating room time is longer than with traditional laparoscopic surgery. Robotic surgery can be considered for giant PPGL if the patient's financial condition permits.