向我的小朋友问好……神经能量学、神经元健康和神经退行性疾病中的微量营养素。

Say hello to my little friend… micronutraceuticals in neuroenergetics, neuronal health, and neurodegenerative diseases.

作者信息

Mason Shayne

机构信息

Human Metabolomics, North-West University, Potchefstroom, South Africa.

出版信息

Front Neurosci. 2025 Apr 23;19:1498655. doi: 10.3389/fnins.2025.1498655. eCollection 2025.

DOI:10.3389/fnins.2025.1498655

PMID:40336537

原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC12055844/

Abstract

Vitamins and minerals (micronutraceuticals) maintain good health. However, the specific effects of these micronutraceuticals on brain health are often overlooked, or not even known. In this review, an overview of the direct and indirect effects of micronutraceuticals on brain energy metabolism (neuroenergetics) and neuronal health is provided. Thereafter, a holistic summary of the existing studies that have shown the impact of micronutraceuticals on neurodegenerative diseases. Lastly, this review concludes by identifying several research gaps that remain and provides suggestions for future research on these hot topics.

摘要

维生素和矿物质（微量营养素）维持身体健康。然而，这些微量营养素对大脑健康的具体影响往往被忽视，甚至不为人知。在本综述中，我们概述了微量营养素对大脑能量代谢（神经能量学）和神经元健康的直接和间接影响。此后，对现有研究进行全面总结，这些研究显示了微量营养素对神经退行性疾病的影响。最后，本综述通过确定仍然存在的几个研究空白得出结论，并为这些热门话题的未来研究提供建议。