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向我的小朋友问好……神经能量学、神经元健康和神经退行性疾病中的微量营养素。

Say hello to my little friend… micronutraceuticals in neuroenergetics, neuronal health, and neurodegenerative diseases.

作者信息

Mason Shayne

机构信息

Human Metabolomics, North-West University, Potchefstroom, South Africa.

出版信息

Front Neurosci. 2025 Apr 23;19:1498655. doi: 10.3389/fnins.2025.1498655. eCollection 2025.

DOI:10.3389/fnins.2025.1498655
PMID:40336537
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC12055844/
Abstract

Vitamins and minerals (micronutraceuticals) maintain good health. However, the specific effects of these micronutraceuticals on brain health are often overlooked, or not even known. In this review, an overview of the direct and indirect effects of micronutraceuticals on brain energy metabolism (neuroenergetics) and neuronal health is provided. Thereafter, a holistic summary of the existing studies that have shown the impact of micronutraceuticals on neurodegenerative diseases. Lastly, this review concludes by identifying several research gaps that remain and provides suggestions for future research on these hot topics.

摘要

维生素和矿物质（微量营养素）维持身体健康。然而，这些微量营养素对大脑健康的具体影响往往被忽视，甚至不为人知。在本综述中，我们概述了微量营养素对大脑能量代谢（神经能量学）和神经元健康的直接和间接影响。此后，对现有研究进行全面总结，这些研究显示了微量营养素对神经退行性疾病的影响。最后，本综述通过确定仍然存在的几个研究空白得出结论，并为这些热门话题的未来研究提供建议。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/8e30/12055844/b6c0f352cbef/fnins-19-1498655-g002.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/8e30/12055844/14689b6ce4cf/fnins-19-1498655-g001.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/8e30/12055844/b6c0f352cbef/fnins-19-1498655-g002.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/8e30/12055844/14689b6ce4cf/fnins-19-1498655-g001.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/8e30/12055844/b6c0f352cbef/fnins-19-1498655-g002.jpg

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本文引用的文献

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Vitamin D Status in Bipolar Disorder.双相障碍中的维生素 D 状况。
Nutrients. 2023 Nov 11;15(22):4752. doi: 10.3390/nu15224752.
2
Mental Health Component Scale Is Positively Associated with Riboflavin Intake in People with Central Obesity.心理健康成分量表与中心性肥胖人群的核黄素摄入量呈正相关。
Nutrients. 2023 Oct 21;15(20):4464. doi: 10.3390/nu15204464.
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Non-Pharmacological Treatment of Primary Headaches-A Focused Review.原发性头痛的非药物治疗——聚焦综述
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The Role of Micronutrients in Neurological Disorders.微量营养素在神经紊乱中的作用。
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Does Decreased Vitamin D Level Trigger Bipolar Manic Attacks?维生素D水平降低会引发双相躁狂发作吗？
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Bioinorganic Chemistry of Micronutrients Related to Alzheimer's and Parkinson's Diseases.与阿尔茨海默病和帕金森病相关的微量元素的生物无机化学
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Dietary riboflavin intake in relation to psychological disorders in Iranian adults: an observational study.饮食核黄素摄入量与伊朗成年人心理障碍的关系：一项观察性研究。
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Long-term dietary folic acid supplementation attenuated aging-induced hippocampus atrophy and promoted glucose uptake in 25-month-old rats with cognitive decline.长期膳食叶酸补充可减轻衰老引起的 25 月龄认知衰退大鼠海马萎缩和促进葡萄糖摄取。
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