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生物医学纳米技术在营养、健康监测和疾病诊断方面的新趋势。

Emerging trends of biomedical nanotechnology in nutrition, health monitoring and disease diagnosis.

作者信息

Arora Palak, Bhagat Stuti, Krishnendu M R, Singh Sanjay

机构信息

Nanobiology and Nanozymology Research Lab, National Institute of Animal Biotechnology (NIAB), Opposite Journalist Colony, Near Gowlidoddy, Extended Q-City Road, Gachibowli, Hyderabad, Telangana 500032 India.

Regional Centre for Biotechnology (RCB), Faridabad, Haryana 121001 India.

出版信息

3 Biotech. 2025 Jun;15(6):152. doi: 10.1007/s13205-025-04291-9. Epub 2025 May 5.

DOI:10.1007/s13205-025-04291-9
PMID:40336812
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC12052695/
Abstract

The transdisciplinary nature of nanotechnology has facilitated its application across various fields, especially in biological sciences. The primary aim of this review is to consolidate the many facets of nanomedicine, theranostics, and nanotechnology in food preservation into a unified framework and to underscore established research methodologies in the medical domain. Nanoparticles serve a crucial function in improving the bioavailability of orally delivered bioactive substances. This review demonstrated that nanoparticles can enhance the bioavailability of micronutrients, such as vitamin B12, vitamin A, folic acid, and iron. New advances in nanotechnology have made big differences in finding pathogens and killing them specifically, helping people to get better health through medication delivery and imaging, improving food packaging better so it lasts longer, and making foods healthier overall. Nanotechnology currently enhances the safety of delivering highly hazardous medicines through the use of nanozymes that exhibit antioxidant and antibacterial characteristics. Moreover, wearable devices can identify significant alterations in vital signs, medical problems, and infections occurring within the body. We anticipate that these technologies will provide physicians with enhanced direct access to crucial information about the causes of changes in vital signs or diseases, as they are directly connected to the source of the problem. This review paper thoroughly examines the latest developments in nanomaterials and nanozymes as antimicrobial agents in food science and nutrition, wound healing, illness diagnostics, imaging, and potential future uses. The paper presents a concise and structured report on nanotechnology, which will be beneficial to researchers and scientists for future research opportunities.

摘要

纳米技术的跨学科性质促进了其在各个领域的应用,尤其是在生物科学领域。本综述的主要目的是将纳米医学、治疗诊断学和食品保鲜中的纳米技术的多个方面整合到一个统一的框架中,并强调医学领域已确立的研究方法。纳米颗粒在提高口服生物活性物质的生物利用度方面发挥着关键作用。本综述表明,纳米颗粒可以提高微量营养素的生物利用度,如维生素B12、维生素A、叶酸和铁。纳米技术的新进展在发现病原体并特异性杀灭它们方面产生了巨大差异,通过药物递送和成像帮助人们获得更好的健康,改善食品包装以使其保质期更长,并使食品总体上更健康。目前,纳米技术通过使用具有抗氧化和抗菌特性的纳米酶提高了递送高危险性药物的安全性。此外,可穿戴设备可以识别体内生命体征、医学问题和感染的重大变化。我们预计,这些技术将为医生提供更直接的途径,获取有关生命体征变化或疾病原因的关键信息,因为它们直接与问题的源头相连。这篇综述论文全面审视了纳米材料和纳米酶作为食品科学与营养、伤口愈合、疾病诊断、成像以及潜在未来用途中的抗菌剂的最新进展。该论文呈现了一份关于纳米技术的简洁且结构化的报告,这将对研究人员和科学家未来的研究机会有所助益。

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本文引用的文献

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Modulating the immune system towards a functional chronic wound healing: A biomaterials and Nanomedicine perspective.调节免疫系统以实现功能性慢性伤口愈合:生物材料和纳米医学视角。
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Empowering Precision Medicine: The Impact of 3D Printing on Personalized Therapeutic.赋能精准医学:3D 打印对个性化治疗的影响。
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Structural and biological engineering of 3D hydrogels for wound healing.用于伤口愈合的3D水凝胶的结构与生物工程
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A broad-spectrum antibacterial and tough hydrogel dressing accelerates healing of infected wound in vivo.一种广谱抗菌且坚韧的水凝胶敷料可加速体内感染伤口的愈合。
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Colorimetric Nanobiosensor Design for Determining Oxidase Enzyme Substrates in Food and Biological Samples.用于测定食品和生物样品中氧化酶底物的比色纳米生物传感器设计
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Aligned electrospun fiber film loaded with multi-enzyme mimetic iridium nanozymes for wound healing.载有多酶模拟铱纳米酶的取向静电纺丝纤维膜用于伤口愈合。
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