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头颈部NUT癌:一例报告及文献综述。

NUT carcinoma of the head and neck: A case report and literature review.

作者信息

Zhao Yue, Zhang Jun, Liao Wenjun, Li Jiayu, Zhang Shichuan

机构信息

Department of Radiation Oncology Radiation Oncology Key Laboratory of Sichuan Province Sichuan Clinical Research Center for Cancer Sichuan Cancer Hospital &Institute Sichuan Cancer Center Affiliated Cancer Hospital of University of Electronic Science and Technology of China Chengdu Sichuan China.

Department of Pathology Sichuan Clinical Research Center for Cancer Sichuan Cancer Hospital & Institute Sichuan Cancer Center Affiliated Cancer Hospital of University of Electronic Science and Technology of China Chengdu China.

出版信息

Precis Radiat Oncol. 2024 Sep 1;8(3):138-144. doi: 10.1002/pro6.1237. eCollection 2024 Sep.

Abstract

Nuclear protein in testis (NUT) carcinoma is a rare and highly aggressive cancer, characterized by rearrangements involving the gene located on chromosome 15q14. In this report, we present the case of a 52-year-old female diagnosed with primary parotid NUT carcinoma. Despite undergoing surgery, adjuvant chemotherapy, and incomplete regional radiotherapy, the patient succumbed to the disease after an overall survival duration of 7 months. We retrospectively discuss patient clinical and pathological features, as well as therapeutic approaches of NUT carcinoma of the head and neck.

摘要

睾丸核蛋白(NUT)癌是一种罕见且侵袭性很强的癌症,其特征是涉及位于15号染色体q14区域的基因重排。在本报告中,我们介绍了一名52岁女性被诊断为原发性腮腺NUT癌的病例。尽管接受了手术、辅助化疗和不完全的局部放疗,但患者在总生存期7个月后死于该疾病。我们回顾性地讨论了患者的临床和病理特征,以及头颈部NUT癌的治疗方法。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/aa8a/11935197/5876e3b1a88f/PRO6-8-138-g005.jpg

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