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子宫颈鳞状细胞癌皮肤转移:一例报告。

Skin metastasis in squamous cell cancer of cervix: A case report.

作者信息

Zhao Xiujuan, Chen Rui, Zhou Qi

机构信息

Department of Gynecological Oncology Center Chongqing University Cancer Hospital Chongqing Chongqing China.

Department of Pathology Department Chongqing University Cancer Hospital Chongqing Chongqing China.

出版信息

Precis Radiat Oncol. 2023 Jun 12;7(2):142-146. doi: 10.1002/pro6.1195. eCollection 2023 Jun.

DOI:10.1002/pro6.1195
PMID:40337263
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC11934991/
Abstract

Cervical cancer, the fourth most common cancer among females in the world, ranks the second in China. In advanced disease, metastases may be commonly present in the lungs, bones, liver and lymph nodes or elsewhere, but uncommon to the skin. In this report, a 63-year-old woman was diagnosed as stage IVB cervical squamous cell cancer in January 2021. The patient was scheduled for concurrent chemoradiotherapy; however, a metastatic lesion of skin was proved by biopsy during the process of treatment. She died 1 month after confirmed skin metastases. Cutaneous metastasis of cervical cancer may predict the mix of lymphatic and hematogenous metastasis and the rapid fatal termination.

摘要

宫颈癌是全球女性中第四大常见癌症,在中国则位居第二。在晚期疾病中,转移灶可能常见于肺部、骨骼、肝脏和淋巴结或其他部位,但皮肤转移并不常见。在本报告中,一名63岁女性于2021年1月被诊断为IVB期宫颈鳞状细胞癌。该患者计划接受同步放化疗;然而,在治疗过程中活检证实存在皮肤转移灶。在确诊皮肤转移1个月后她死亡。宫颈癌的皮肤转移可能预示着淋巴转移和血行转移的混合情况以及快速致命的结局。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/ae27/11934991/02109c078280/PRO6-7-142-g005.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/ae27/11934991/2b01008bbd56/PRO6-7-142-g003.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/ae27/11934991/b46556692c9d/PRO6-7-142-g002.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/ae27/11934991/53443b7afdfe/PRO6-7-142-g001.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/ae27/11934991/02109c078280/PRO6-7-142-g005.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/ae27/11934991/2b01008bbd56/PRO6-7-142-g003.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/ae27/11934991/b46556692c9d/PRO6-7-142-g002.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/ae27/11934991/53443b7afdfe/PRO6-7-142-g001.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/ae27/11934991/02109c078280/PRO6-7-142-g005.jpg

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本文引用的文献

1
A case report of carcinoma of uterine cervix throwing heterochronous metastasis to the skin, spleen, and pancreas: the role of multimodality treatment approach.一例子宫颈癌发生异时性皮肤、脾脏和胰腺转移的病例报告:多模式治疗方法的作用
J Egypt Natl Canc Inst. 2019 Dec 16;31(1):8. doi: 10.1186/s43046-019-0009-9.
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Scalp and skull bone metastasis in cervical carcinoma-a rare entity.宫颈癌的头皮及颅骨转移——一种罕见情况。
Ecancermedicalscience. 2019 Oct 17;13:969. doi: 10.3332/ecancer.2019.969. eCollection 2019.
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2018 年宫颈癌发病率和死亡率的估计:全球分析。
Lancet Glob Health. 2020 Feb;8(2):e191-e203. doi: 10.1016/S2214-109X(19)30482-6. Epub 2019 Dec 4.
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Curr Probl Cancer. 2018 Sep;42(5):527-533. doi: 10.1016/j.currproblcancer.2018.04.004. Epub 2018 May 23.
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Advanced cervical squamous cell carcinoma with skin metastasis.晚期宫颈鳞状细胞癌伴皮肤转移。
Taiwan J Obstet Gynecol. 2007 Sep;46(3):264-6. doi: 10.1016/S1028-4559(08)60031-5.
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A review of hypofractionated palliative radiotherapy.短程姑息性放射治疗综述
Cancer. 2007 Apr 15;109(8):1462-70. doi: 10.1002/cncr.22555.
10
Incisional skin metastasis of a squamous cell cervical carcinoma 3.5 years after radical treatment--a case report.根治性治疗3.5年后宫颈鳞状细胞癌的切口皮肤转移——病例报告
Int J Gynecol Cancer. 2005 Nov-Dec;15(6):1183-6. doi: 10.1111/j.1525-1438.2005.00173.x.